Case management of malaria in Swaziland, 2011–2015: on track for elimination?

Dlamini, Sabelo; Kosgei, Rose J.; Mkhonta, Nomcebo; Zulu, Z; Makadzange, K; Zhou, Shui-Sen; Owiti, Philip; Sikhondze, Welile; Namboze, Josephine M.; Reid, Anthony; Kunene, Simon

doi:10.5588/pha.17.0047

Cited by 6 publications

(9 citation statements)

References 21 publications

(21 reference statements)

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“…Also, one in four in-patients who received at least one in-hospital dose of prescribed anti-malarials missed the first day of their anti-malarial treatment. The missed treatment could be worsened by the observed disparities in prescribed, dispensed and administered anti-malarials—similar to observations made elsewhere [ 8 , 10 ]. Possible reasons for these system lapses include; (i) drug stock-outs, (ii) poor communication between clinician and patient/caregiver and, (iii) work overload [ 3 ].…”

Section: Discussionsupporting

confidence: 79%

“…It is necessary for patients with severe malaria to initiate timely appropriate anti-malarials and complete full courses of prescribed anti-malarials, which promotes therapeutic success, reduces malaria-related mortality and prevents drug resistance [ 7 – 9 ]. However, SSA patients with severe malaria frequently receive incomplete doses of prescribed anti-malarials and/or treatment meant for uncomplicated malaria [ 8 , 10 ]. One-third of hospitalized Ugandan patients missed Day 1 of prescribed antibiotics [ 3 ], but similar data are scarce on anti-malarial use.…”

Section: Introductionmentioning

confidence: 99%

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Quality of care for adult in-patients with malaria in a tertiary hospital in Uganda

Kiguba

Karamagi

Bird

2021

Malar J

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Background Prompt detection and appropriate treatment of malaria prevents severe disease and death. The quality of care for adult malaria in-patients is not well documented in sub-Saharan Africa, particularly in Uganda. The study sought to describe the patterns of malaria diagnosis and treatment among adult in-patients admitted to the medical and gynaecological wards of Uganda’s 1790-bed Mulago National Referral Hospital from December 2013 to April 2014. Methods A prospective cohort of 762 consented in-patients aged ≥ 18 years was assembled. Proportions of in-patients who received preadmission and in-hospital anti-malarials, missed Day 1 dosing of hospital-initiated anti-malarials and/or had malaria microscopy done were determined. Multivariable logistic regression was used to identify risk-factors for missed Day 1 dosing of anti-malarials. Results One in five (19%, 146/762) in-patients had an admission or discharge malaria diagnosis or both; with median age of 29 years (IQR, 22–42 years). Microscopy was requested in 77% (108/141) of in-patients with an admission malaria diagnosis; results were available for 46% (50/108), of whom 42% (21/50) tested positive for Plasmodium falciparum malaria parasitaemia. Only 13% (11/83) of in-patients who received in-hospital injectable artesunate (AS) or quinine (Q) received follow-up oral artemether-lumefantrine (AL); 2 of 18 severe malaria cases received follow-up oral AL. Injectable AS only (47%, 47/100) was the most frequent hospital-initiated anti-malarial treatment followed by injectable Q only (23%, 23/100) amongst in-patients who received in-hospital anti-malarials. A quarter (25%, 25/100; 95% CI: 17–35%) of in-patients missed Day 1 dosing of hospital-initiated anti-malarials. Each additional admission diagnosis was more than two-fold likely to increase the odds of missed Day 1 dosing of in-hospital anti-malarials (aOR = 2.6, 95% CI: 1.52–4.56; P-value = 0.001). Conclusions Half the malaria microscopy results were not available; yet, the rate of testing was high. The majority of in-patients initiated on injectable AS or Q did not receive the recommended follow-up oral AL. One in four in-patients delayed to initiate hospital anti-malarials by at least one calendar day. The hospital should encourage prompt availability of malaria test-results to promote the timely initiation and completion of anti-malarial treatment, thereby improving the quality of care for hospitalized malaria patients in Uganda.

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Section: Discussionsupporting

confidence: 79%

Section: Introductionmentioning

confidence: 99%

Quality of care for adult in-patients with malaria in a tertiary hospital in Uganda

Kiguba

Karamagi

Bird

2021

Malar J

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“…This confirms some of the work in sports marketing that has shown that BSR can improve the attitudes of sports enthusiasts, their intention to return and generate positive WOM (Filo et al, 2008;Kim et al, 2010). Mazzarol et al (2007) health knowledge than men (Dlamini et al, 2018;Shin & Matilla, 2019). This is consistent with Dlamini et al (2018), who also determined that women continue to have higher levels of environmental concern, environmental attitudes, health awareness and concern for animal welfare.…”

Section: Discussionsupporting

confidence: 76%

Perceptions of ethical cosmetics: Health behaviors during the COVID‐19 pandemic

Delannoy

Baudier²,

Vassoigne³

2023

J of Consumer Behaviour

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Ethical consumption is considered one of the key issues of the early twenty‐first century, and the demand for natural and chemical‐free products has continued to grow. This study aims to explore consumers' perceptions of ethical cosmetics during the COVID‐19 pandemic; measuring the self‐dimensions that influence their opinions on the potential benefits of healthy cosmetics and measuring these impacts on purchase intention and purchase recommendation. A survey of 483 qualified respondents was conducted through a market research company. The research model, which mobilized constructs drawn from the literature, was analyzed using a partial least square approach via SmartPLS3.3.9 software. Our results demonstrate the direct impact of brand social responsibility (BSR), personal‐positive (PP), and social‐positive (SP) on word‐of‐mouth (WOM). The influence of self‐association on PP is validated but rejected for SP. We show that extended‐self has a direct effect on PP but not on SP, while self‐design has an impact on both variables. Finally, the variables SP, PP, and BSR have a direct impact on the intention to buy healthy cosmetics but not on the WOM construct. As such, this study contributes to the literature on the perception of ethical/healthy cosmetics and consumer behavior and perceptions.

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“…In this study, microscopy, a gold standard test, was used to confirm malaria in most of the cases. However, in previous studies from Swaziland and Zimbabwe, RDT was used to confirm malaria in the majority of cases [14, 15]. Almost all patients in this study were tested positive and only 2 cases tested negative.…”

Section: Discussionmentioning

confidence: 70%

Severe malaria management: current situation, challenges and lessons learned from Gezira State, Sudan

Elnour

Alagib

Bansal

et al. 2019

Malar J

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Background The present study aimed to evaluate the management of severe malaria at Gezira State hospitals in Sudan by assessing hospital readiness, health care provider knowledge and the care received by severe malaria patients. Methods A cross-sectional descriptive study was performed to assess the severe malaria management practices at hospitals level in Gezira State. The study population included hospitals, health care providers and patients. Data was collected using checklists and structured questionnaires. Results A total of 20 hospitals, 158 health care providers and 370 patients were included in the study. Out of the total hospitals, 95% (19/20) were providing 24 h outpatient services, 65% (13/20) had ICU units, while triage system was found in only 35% (7/20) of hospitals. From all hospitals evaluated, 90% (18/20) were suffering from shortage of staff, especially doctors. About half of the health care providers (46.7%) did not receive severe malaria management training. The average knowledge score among health care providers was 55.4%. Microscopy was available in all hospitals (100%), while rapid diagnostic test, complete blood count and renal function test were available in 15 hospitals (75%). Fever was the most presenting symptom (97.8%) followed by repeated vomiting (51.4%), convulsion in children (24.3%) and prostration in adult (57.9%). Correctly diagnosed patients were 68.9%. Essential tests were done for only 11.1% of patients. Majority of patients (91.7%) were treated with quinine, 5.9% received artemether, while 2.4% were treated with artemether–lumefantrine. Those who received both the correct dose and dosing regimen were 53.8%. The overall compliance to guidelines was 2.2%. Conclusion This study highlights the fact that management of severe malaria at hospital level was suboptimal with serious shortcomings in the different aspects of care particularly in specialized hospitals. Technical staff was inadequate, hospitals were anguish from defective emergency services, and most patients were not treated according to the national guidelines. Electronic supplementary material The online version of this article (10.1186/s12936-019-2805-z) contains supplementary material, which is available to authorized users.

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Case management of malaria in Swaziland, 2011–2015: on track for elimination?

Cited by 6 publications

References 21 publications

Quality of care for adult in-patients with malaria in a tertiary hospital in Uganda

Quality of care for adult in-patients with malaria in a tertiary hospital in Uganda

Perceptions of ethical cosmetics: Health behaviors during the COVID‐19 pandemic

Severe malaria management: current situation, challenges and lessons learned from Gezira State, Sudan

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