Case–control Study of Risk Factors for No Light Perception After Open-Globe Injury

Abstract

Ciliary body damage, closed funnel retinal detachment, and choroidal damage are independent risk factors for NLP posttrauma but not prognostic indicators for NLP visual outcome. Traumatized eyes with NLP may recover light perception or better vision if appropriate interventional measures are used for treatment of the injured ciliary body, retina, and choroid.

Clinical features and outcomes of vitrectomy in pediatric ocular injuries-eye injury vitrectomy study

“…The details of EIVS database setup has been described by Feng K.[1011] In this study, the inclusion criteria were: (1) children aged 15 years and below; (2) the minimum follow-up was 6 months. Cases with missing records were excluded.…”

“…All these features were recorded in the database of EIVS as introduced by Feng et al . [1011] Follow-up information, including the follow-up period, best-corrected visual acuity (BCVA) and intraocular pressure (IOP) at the last visit, tamponade of vitreous cavity, and anatomical outcome, was recorded at outpatient after follow-up no less than 6 months. The anatomical and visual outcomes were evaluated and predictive factors of unfavorable outcome were analyzed using multiple logistic regressions.…”

Development of medical treatment for eye injuries in the mainland of China over the past decade

“…However, it is unknown which tissue injuries are critical and which degree of injuries can cause lethal damage to the globe, as the great individual difference among the injured eyes makes it difficult to draw a general rule according to ophthalmologists' personal practice. The results of multicenter controlled study reveal the secret that has been present for a long period of time: a) The ciliary body, choroid and retina are three key parts of the eye with NLP, and serious eye injury may be concurrently involved with the injury of the three tissues or mainly involved with one or two tissues4, 5; b) The three key tissues, if seriously damaged, are characterized by the injury of ciliary body tissues (such as extensively damaged ciliary process, epithelial exfoliation and extensive centripetal ciliary body detachment), the severely injured choroid (such as tearing, expulsive suprachoroidal hemorrhage and retinal pigment epithelium exfoliation), and the closed funnel-shaped retinal detachment.Key problems to be tackled in the treatment for the severely injured eye…”

Approach to management of eyes with no light perception after open globe injury

“…[3456789101112] Unfortunately, optic nerve avulsion can be difficult to confirm in the setting of severe globe trauma because the dural sheath often remains attached to the globe even if retrolaminal neural tissue is disrupted. [131415] In contrast to a complete optic nerve transection, an optic nerve avulsion may be partial, and partial return of visual function has been documented in some cases.…”

“…[12] Loss of light perception (LP) after open globe injury, however, does not necessarily mean that the patient will have permanent visual loss. [3456789101112] Reported visual recovery rates from NLP to LP or better after globe rupture range from 4%-33%. [3456789101112] In one study of 73 NLP eyes (73 patients) with OGI that underwent primary repair, final visual acuity was LP or better in 17 (23%) eyes.…”