Case–control study of nutritional and environmental factors and the risk of oral clefts in Thailand

McKinney, Christy M.; Pisek, Araya; Chowchuen, Bowornsilp; DeRouen, Timothy A.; Muktabhant, Benja; Pradubwong, Suteera; Yeung, Cathy; Pitiphat, Waranuch

doi:10.1002/bdra.23505

Cited by 20 publications

(25 citation statements)

References 34 publications

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“…Although the correlation between secondhand smoke and CMs has been a concern for several decades, different studies obtained somewhat different results . Most studies reported a significantly increased risk for cardiovascular system malformations, whereas a study by Wasserman et al did not .…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, study results regarding the association have been inconsistent. Some studies suggested that exposure to secondhand smoke in nonsmoking women significantly increases the risk of CMs in their offspring, whereas others showed no relation or even a protective effect . In 2010, two meta‐analyses were conducted to examine the association between secondhand smoke and CMs .…”

Section: Introductionmentioning

confidence: 99%

“…Since those meta‐analyses, however, many original studies related to this topic have emerged. Many of these studies were conducted in different regions and have investigated the association between secondhand smoke and organ‐system malformations . It is therefore possible to conduct an updated comprehensive assessment based on the new and previously existing evidence.…”

Section: Introductionmentioning

confidence: 99%

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Congenital malformations are associated with secondhand smoke among nonsmoking women: A meta‐analysis

Zheng

Xie

Yang

et al. 2018

Birth

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Background The association between active maternal smoking and congenital malformations is well established, but little is known about the association between secondhand smoke and congenital malformations. Moreover, studies regarding the association between congenital malformations and secondhand smoke have not yielded consistent results. Methods In July 2018, we searched PubMed, EMBASE, and China Biology Medicine databases for observational studies characterizing the relationship between secondhand smoke and congenital malformations of offspring in nonsmoking women. Two reviewers independently decided on whether a study should be included, did data extraction, and assessed study quality. Pooled risks with 95% confidence intervals were calculated using either the fixed‐effects models or random‐effects models. Further subgroup analyses and sensitivity analyses were performed to explore the potential source of heterogeneity and to examine the robustness of risk estimates. Results Thirty‐three studies with a total of 31 944 cases and 32 335 controls were included. Secondhand smoke exposure was associated with an increased risk of congenital malformations (odds ratio = 1.92; 95% confidence interval 1.61‐2.30). Secondhand smoke was correlated with significantly increased risk for digestive system (1.17 [1.05‐1.32]), nervous system (1.74 [1.33‐2.29]), and cardiovascular system (2.10 [1.32‐3.35]) malformations and for oral clefts (1.87 [1.47‐2.39]). Conclusions Secondhand smoke exposure increases the risk for overall and several organ‐system malformations. These findings highlight the necessity of improving community awareness to prevent secondhand smoke exposure during the preconception and conception periods.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Congenital malformations are associated with secondhand smoke among nonsmoking women: A meta‐analysis

Zheng

Xie

Yang

et al. 2018

Birth

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“…This is especially true for cleft lip and/or palate, which are the most frequent congenital craniofacial malformations. Cohort and case control studies have identified certain environmental factors as risk factors, including alcohol, smoking and excessive intake of vitamin A (DeRoo et al, ; Kummet et al, ; McKinney et al, ). One cohort study revealed that smoking during pregnancy is a risk factor for isolated CA (Kancherla et al, ).…”

Section: Amniotic Band Constrictionmentioning

confidence: 99%

Choanal atresia and stenosis: Development and diseases of the nasal cavity

Kurosaka

2018

WIREs Developmental Biology

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Proper craniofacial development in vertebrates depends on growth and fusion of the facial processes during embryogenesis. Failure of any step in this process could lead to craniofacial anomalies such as facial clefting, which has been well studied with regard to its molecular etiology and cellular pathogenesis. Nasal cavity invagination is also a critical event in proper craniofacial development, and is required for the formation of a functional nasal cavity and airway. The nasal cavity must connect the nasopharynx with the primitive choanae to complete an airway from the nostril to the nasopharynx. In contrast to orofacial clefts, defects in nasal cavity and airway formation, such as choanal atresia (CA), in which the connection between the nasal airway and nasopharynx is physically blocked, have largely been understudied. This is also true for a narrowed connection between the nasal cavity and the nasopharynx, which is known as choanal stenosis (CS). CA occurs in approximately 1 in 5,000 live births, and can present in isolation but typically arises as part of a syndrome. Despite the fact that CA and CS usually require immediate intervention, and substantially affect the quality of life of affected individuals, the etiology and pathogenesis of CA and CS have remained elusive. In this review I focus on the process of nasal cavity development with respect to forming a functional airway and discuss the cellular behavior and molecular networks governing this process. Additionally, the etiology of human CA is discussed using examples of disorders which involve CA or CS. This article is categorized under: Signaling Pathways > Cell Fate Signaling Comparative Development and Evolution > Model Systems Birth Defects > Craniofacial and Nervous System Anomalies

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“…In humans, plasma zinc concentration (PZn) is affected by many factors such as smoking, drinking alcohol, diabetes, and drug consumption such as 6‐mercaptopurine, thalidomide, and valproic acid (Uriu‐Adams & Keen, ). However, there is no consensus between plasma zinc status in pregnant women and the risk of NSCL/P in their offspring (Hozyasz et al, ; Krapels et al, ; McKinney et al, ; Munger et al, ; Shaw, Carmichael, Laurent, & Rasmussen, ; Tamura et al, ). Ideally, in order to evaluate this association, maternal zinc levels should be analyzed at the critical time of lip and primary palate formation is around six weeks of gestational age (Mossey, Little, Munger, Dixon, & Shaw, ; Sperber, ).…”

Section: Introductionmentioning

confidence: 99%

Plasma zinc levels in Ecuadorian mothers of infants with nonsyndromic cleft lip with or without cleft palate: A case series

Jara-Palacios

Cornejo

Narváez-Caicedo

et al. 2018

Birth Defects Research

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Background: Previous studies have reported an association between maternal zinc deficiency and increased risk of nonsyndromic cleft lip with or without cleft palate (NSCL/P) in offspring. A high prevalence of zinc deficiency and a high prevalence of NSCL/P have been reported in Ecuador. We postulated that mothers of infants with NSCL/P may have lower serum zinc levels than women from the general population.

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Case–control study of nutritional and environmental factors and the risk of oral clefts in Thailand

Cited by 20 publications

References 34 publications

Congenital malformations are associated with secondhand smoke among nonsmoking women: A meta‐analysis

Congenital malformations are associated with secondhand smoke among nonsmoking women: A meta‐analysis

Choanal atresia and stenosis: Development and diseases of the nasal cavity

Plasma zinc levels in Ecuadorian mothers of infants with nonsyndromic cleft lip with or without cleft palate: A case series

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