Case-Control Study of Iron Deficiency Anaemia in Febrile Seizures

Potdar, Shailaja Milind; Junagade, Sunil Vijay; Panot, Jayesh; Kumavat, Vandana; Rojekar, Mohit Vijay; Malgaonkar, Aniruddha A.; Bhusare, Madhuri

doi:10.14260/jemds/2017/1021

Cited by 2 publications

(2 citation statements)

References 6 publications

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“…Compared to our study, which also showed low serum ferritin & MCV in the study group, the above study did not entail regarding RDW which was increased in our study [12] . Shailaja potdar et al concluded that serum ferritin and Haemoglobin were significantly low and RDW was high in children with febrile seizures which is on par to our study [13] . Yousefichaijan P et al also showed similar results as our study with low MCV and serum ferritin.…”

Section: Methodssupporting

confidence: 84%

Correlation of serum ferritin levels and RBC indices in children with febrile seizures

M¹,

Cs²,

Chidambaranathan³

2019

Int. J. Paediatrics Geriatrics

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Background: Febrile seizures are the most common seizures that occur in 2 to 5% of neurologically healthy children in the age group of 6 -60 months. There is an increased risk of febrile seizures in Children with iron deficiency anaemia. Iron deficiency anaemia is also associated with impaired neurocognitive functions. Our study compares the haematological parameters in children with febrile seizures. Methods:The study is a prospective study conducted in a tertiary care hospital. Children admitted with first episode of febrile seizures in the age group of 6-60 months were included in study group. Total of 50 children were enrolled in the study. Duration of study was one year. Haemoglobin levels, Red Blood Cell indices and serum ferritin were studied among the children and statistically analysed. Results: The study showed that haemoglobin levels, RBC indices particularly Mean Corpuscular Volume( MCV) was low in 100% and Red Cell Distribution Width (RDW) was increased in 96% of children with low ferritin levels depicting iron deficiency anaemia, which in turn is a risk factor for febrile seizures. Conclusion:The study concluded that among the RBC indices, RDW and MCV values well correlated with serum ferritin levels in detecting iron deficiency anaemia in children with first episode of febrile seizures.

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Section: Methodssupporting

confidence: 84%

Correlation of serum ferritin levels and RBC indices in children with febrile seizures

M¹,

Cs²,

Chidambaranathan³

2019

Int. J. Paediatrics Geriatrics

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“…These studies suggested that inflammatory cytokines, especially IL-1β, IL-6 and TNF-α can play important role in the generation of FS. Although inflammatory cytokines are useful biomarkers, their increased cost and limited availability are drawbacks [3][4][5][6][7][8][9].…”

Section: Introductionmentioning

confidence: 99%

A Study on Haematological Parameters in Febrile Seizures

Obi¹,

Ravichander

2023

PIJR

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Febrile seizures are the most common neurologic disorder in the pediatric age group, affecting 2–5% of children between 6 months and 5 years of age in the United States and Western Europe with a peak incidence between 12 and 18 months. Although febrile seizure is seen in all ethnic groups, it is more frequently seen in the Asian population (5–10% of Indian children and 6–9% of Japanese children). Systemic inflammatory response has been implicated as a contributor to the onset of febrile seizure [1]. It is studied that IL-B, IL-6, TNF-ALPHA can play an important role in generation of febrileseizure. Although they are the useful biomarkers, its availability in day to day practice is very limited. So there is a need for low cost and widely used inflammatory response markers like NLR, MPV, PLT, and RDW as independent predictors of febrile seizure and to compare different Hematological parameters in febrile seizure in patients with an unclear seizure history. The 5 novel indices of inflammatory response: i. Neutrophil Lymphocyte Ratio ii. Mean Platelet Volume iii. Platelet Count Ratio iv. Red cell Distribution Width v. Serum Ferritin The study is carried out for the assessment of other hematological parameters in febrile seizures like HB, RBC, PCV, RDW, Platelets, MPV and PCR. Also to compare the variation of hematological parameters in simple and complex febrile seizures based on the laboratory parameters which are otherwise classified clinically.

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Case-Control Study of Iron Deficiency Anaemia in Febrile Seizures

Cited by 2 publications

References 6 publications

Correlation of serum ferritin levels and RBC indices in children with febrile seizures

Correlation of serum ferritin levels and RBC indices in children with febrile seizures

A Study on Haematological Parameters in Febrile Seizures

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