“…There was a significant reduction in influenza R 0 from 1.91 (95% CI 1.50 to 2.36) before prophylactic intervention to 0.11 after intervention (95% CI 0.05 to 0.20; Bayesian posterior hypothesis p<0.001) [37] . Meta-analysis of oseltamivir prophylaxis for individual protection irrespective of study design, influenza strain and combining pre- and post-exposure studies showed the pooled odds of laboratory confirmed influenza was statistically significantly lower compared to placebo or no therapy (n = 8 studies [27] – [29] , [34] , [35] , [37] , [38] , [41] ; OR = 0.11; 95% CI 0.06 to 0.20; p<0.001; I 2 = 58.7%; see Fig. 3 ).…”