“…PSMA PET/CT also has limitations in the detection of local recurrence since benign prostatic pathologies such as focal prostatitis, benign prostatic hyperplasia and even normal prostate can show areas of increased uptake (6,7). Some strategies such as interval increased activity on delayed PSMA PET/CT scan can suggest malignancy in equivocal cases (8). Also, studies have shown that imaging and biopsy results can evolve post-radiation (9,10).…”