We prove new inequalities concerning Brauer's k(B)-conjecture and Olsson's conjecture by generalizing old results. After that, we obtain the invariants for 2-blocks of finite groups with certain bicyclic defect groups. Here, a bicyclic group is a product of two cyclic subgroups. This provides an application for the classification of the corresponding fusion systems in a previous paper. To some extent, this generalizes previously known cases with defect groups of types D 2 n × C 2 m , Q 2 n × C 2 m and D 2 n * C 2 m. As a consequence, we prove Alperin's weight conjecture and other conjectures for several new infinite families of nonnilpotent blocks. We also prove Brauer's k(B)-conjecture and Olsson's conjecture for the 2-blocks of defect at most 5. This completes results from a previous paper. The k(B)-conjecture is also verified for defect groups with a cyclic subgroup of index at most 4. Finally, we consider Olsson's conjecture for certain 3-blocks.