Carriers of Hemophilia A

Nilsson, Inga Marie; Blombäck, Margareta; Thilén, Astrid; Francken, Irene V.

doi:10.1111/j.0954-6820.1959.tb14510.x

Search citation statements

Order By: Relevance

Paper Sections

Select...

Discussion1

Methods1

Citation Types

Supporting

Mentioning

Contrasting

Year Published

1962

2023

Publication Types

Select...

Article4

Book3

Relationship

Self Cite1

Independent6

Authors

Journals

Cited by 50 publications

(2 citation statements)

References 34 publications

(22 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Hysterectomy in 11: 5 was complicated by increased bleeding. In I1 : 9 caesarean section was not attended by any undue loss of blood, possibly because the AHF is normally increased during pregnancy (20).…”

Section: Discussionmentioning

confidence: 99%

On a Swedish Family with 51 Members Affected by von Willebrand's Disease

Silwer¹,

Nilsson²

1964

Journal of Internal Medicine

Self Cite

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

On a Swedish Family with 51 Members Affected by von Willebrand's Disease

Silwer¹,

Nilsson²

1964

Journal of Internal Medicine

Self Cite

View full text Add to dashboard Cite

“…Thrombin (Topostasin, Roche, Basle, Switzerland). Citrated plasma was prepared as described by Nilsson et al (1959). The end split products D and E and the high molecular weight split (HMWS) products of fibrinogen were prepared as reported earlier (NilChn 1967a/b).…”

Section: Methodsmentioning

confidence: 99%

Influence of Split Products of Fibrinogen on Results of Blood Coagulation Tests and Platelet Adhesiveness

Niléhn¹

1967

Scandinavian Journal of Haematology

View full text Add to dashboard Cite

The effect of high molecular weight split (HMWS) products and D and E products on the determination of one‐stage prothrombin time, prothrombin and proconvertin, factors V, VIII, and IX, platelet adhesiveness and the thrombin time was investigated. When the concentration of the split products (D, E or HMWS) was 0.5–1.0 mg per ml plasma or less, the thrombin time was only slightly prolonged, and the results of other tests studied, platelet adhesiveness included, were not affected significantly. Prolonged thrombin time and one‐stage prothrombin time and a decrease to half of the normal factor V value were noted when the concentration of the HMWS products was increased to 5–10 mg per ml plasma, while the P & P value was influenced only slightly. When the concentrations of the split products exceeded the maximal level achievable in vivo was a large effect noted on factor V and some effect on P & P. The HMWS products probably act partly as ‘antithrombin’, partly as inhibitor of the polymerization of the fibrin monomer, while the D and E products act only as ‘antithrombins’. The esterolytic effect of thrombin on TAME was not inhibited by D and E products in a molar concentration of 1/7 and 1/5, respectively, of that of TAME.

show abstract

History of Classical Hemophilia in a New England Family

McKusick¹

1962

Arch Intern Med

View full text Add to dashboard Cite

Carriers of Hemophilia A

Cited by 50 publications

References 34 publications

On a Swedish Family with 51 Members Affected by von Willebrand's Disease

On a Swedish Family with 51 Members Affected by von Willebrand's Disease

Influence of Split Products of Fibrinogen on Results of Blood Coagulation Tests and Platelet Adhesiveness

History of Classical Hemophilia in a New England Family

Contact Info

Product

Resources

About