Carpal Tunnel Syndrome Caused by Space Occupying Lesions

Kang, Ho‐Jung; Jung, Sung-Hoon; Choi, Christine; Choi, Woo-Jin; Kim, Sung-Jae; Hahn, Soo-Bong

doi:10.4055/jkoa.2007.42.5.616

Cited by 19 publications

(28 citation statements)

References 16 publications

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“…Similarly, gout is also known to cause inflammation in soft tissues and to produce gouty tophi, which can cause CTS. 36,37 In previous studies, gout was reported to be a comorbidity associated with CTS, 36,38 and this claim is consistent with our findings.…”

supporting

confidence: 93%

Validation of known risk factors associated with carpal tunnel syndrome: A retrospective nationwide 11-year population-based cohort study in South Korea

Lee¹,

Lim²,

Kim³

2018

Preprint

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QuestionWhat is the relationship between the previously known risk factors and occurrence of carpal tunnel syndrome (CTS)? FindingsIn this retrospective population-based cohort study that included 512,942 participants sampled from the Korean National Health Insurance System database, we determined the following known risk factors were related to the occurrence of CTS: the age of 40s, female, being overweight, diabetes, rheumatoid arthritis, gout, and Raynaud's syndrome. However, ESRD, hypothyroidism and smoking were not correlated with CTS occurrence. Implications. CC-BY-NC-ND 4.0 International license peer-reviewed) is the author/funder. It is made available under a The copyright holder for this preprint (which was not . http://dx.doi.org/10.1101/253666 doi: bioRxiv preprint first posted online Jan. 26, 2018; 3We identified the age of 40s, female, overweight, diabetes, rheumatoid arthritis, gout, and Raynaud's syndrome as risk factors for the occurrence of CTS. Abstract ImportanceThere have been few large-scale studies that have included a risk factor analysis for CTS.No prior study has investigated and validated the relationship between the occurrence of CTS and known risk factors using nationwide health care database. ObjectiveTo confirm the actual risk factors for CTS out of various known risk factors DesignWe conducted this study using a retrospective cohort model based on the combined two databases of the Korean National Health Insurance System; the national periodic health SettingA population-based retrospective cohort study.. CC-BY-NC-ND 4.0 International license peer-reviewed) is the author/funder. It is made available under aThe copyright holder for this preprint (which was not . http://dx.doi.org/10.1101/253666 doi: bioRxiv preprint first posted online Jan. 26, 2018; Main Outcomes and MeasuresDesired outcomes were the incidence rate of CTS in patients with various risk factors and the hazard ratios of risk factors affecting the disease's occurrence. ResultsThe incidence of CTS was highest in patients in the age of 40s, in the moderate obesity group, in females, and in patients with diabetes mellitus (DM). The hazard ratio analysis revealed that the following risk factors were strongly related to the occurrence of CTS: age of 40s, female, obesity, DM, rheumatoid arthritis, gout, and Raynaud's syndrome. However, ESRD, hypothyroidism and smoking were not correlated with CTS occurrence. Conclusions and RelevanceIn our large-scale cohort study, risk factors such as being in one's 40s, obesity, being female, suffering from DM, and rheumatoid arthritis were reaffirmed as those of CTS occurrence.

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supporting

confidence: 93%

Validation of known risk factors associated with carpal tunnel syndrome: A retrospective nationwide 11-year population-based cohort study in South Korea

Lee¹,

Lim²,

Kim³

2018

Preprint

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“…To justify that, we searched and found several studies listed in the literature that argument in favour of the use of the ultrasound DeltaCSA in the diagnosis of CTS. Ultrasound can be used to identify space-occupying lesions in and around the median nerve, confirm abnormalities in the median nerve (Kang, Jung, Yoon, Hahn, & Kim, 2009) that can be diagnostic of CTS, and help guide injections into the carpal tunnel (Lee, Park, Park, Lee, & Lim, 2014). More specifically, according to a controlled clinical trial by Leonard, Rangan, Doyle, and Taylor (2003) and a meta-analysis by Fowler, Gaughan, and Ilyas (2011), diagnostic ultrasonography can be utilized in detecting accurately the CTS.…”

Section: Discussionmentioning

confidence: 99%

Platelet‐rich plasma ultrasound‐guided injection in the treatment of carpal tunnel syndrome: A placebo‐controlled clinical study

Malahias

Nikolaou

Johnson

et al. 2017

J Tissue Eng Regen Med

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The purpose of this study is to demonstrate whether and to what extent a single injection of platelet-rich plasma (PRP), under ultrasound guidance, can improve the clinical symptoms of patients with a mild to moderate carpal tunnel syndrome (CTS). We conducted a prospective, randomized, clinical study including 50 patients suffering from mild to moderate CTS for a minimum duration of 3 months. Patients were randomly divided into 2 groups: Group A (26 patients) received an ultrasound-guided PRP injection into the carpal tunnel, whereas Group B (24 patients) was injected with placebo (0.9% normal saline). The short- and mid-term outcomes were determined with the use of the Q-DASH questionnaire and the pain scale VAS administered at 0, 4, and 12 weeks follow-up. The success ratio was determined by the difference in the Q-DASH obtained pre-injection minus the final Q-DASH obtained after 12 weeks follow-up. Success was defined as a difference more than 25%. Group A patients demonstrated a 76.9% success as determined by the difference Q-DASH, whereas Group B patients demonstrated 33.3% success, which was significantly less than Group A (Χ , p = .011). The findings of this study suggest that a single PRP ultrasound-guided injection has positive effects in patients with CTS.

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“…The relationship between gout and CTS has been well documented [19,20]. Kang et al [20] reported that tophus deposition in the carpal tunnel can lead to CTS.…”

Section: Comorbiditiesmentioning

confidence: 99%

“…The relationship between gout and CTS has been well documented [19,20]. Kang et al [20] reported that tophus deposition in the carpal tunnel can lead to CTS. In addition, imaging studies have shown the presence of tophi in the floor of the carpal tunnel, carpal bones, radiocarpal joint, and extensor tendons or tendon sheaths of the wrist [19].…”

Section: Comorbiditiesmentioning

confidence: 99%

Medical and non‐medical correlates of carpal tunnel syndrome in a Taiwan cohort of one million

Tseng

Liao²,

Kuo³

et al. 2011

Euro J of Neurology

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Carpal Tunnel Syndrome Caused by Space Occupying Lesions

Cited by 19 publications

References 16 publications

Validation of known risk factors associated with carpal tunnel syndrome: A retrospective nationwide 11-year population-based cohort study in South Korea

Validation of known risk factors associated with carpal tunnel syndrome: A retrospective nationwide 11-year population-based cohort study in South Korea

Platelet‐rich plasma ultrasound‐guided injection in the treatment of carpal tunnel syndrome: A placebo‐controlled clinical study

Medical and non‐medical correlates of carpal tunnel syndrome in a Taiwan cohort of one million

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