Carotid Intima Media Thickness and Its Association With Total Bilirubin Levels in Patients With Coronary Artery Ectasia

Abstract

Atherosclerosis plays an important role in the etiopathogenesis of coronary artery ectasia (CAE). The relationship between total bilirubin (TBil) and carotid intima media thickness (cIMT) in patients with CAE has not been fully investigated. Hence, we evaluated the relationship between TBil levels and cIMT in 142 consecutive eligible patients with CAE, newly diagnosed coronary artery disease (CAD), and normal coronary arteries. There were no significant differences in TBil (P = .772) and cIMT (P = .791) between the CAE and CAD groups. Bilirubin levels were significantly lower in both CAE and CAD groups compared to the controls (P < .01). The cIMT was significantly higher in both CAE and CAD groups compared to control participants (P < .01). A negative correlation between cIMT and TBil was found in all the groups (P < .01, r = .354). We show for the first time that patients with CAE and CAD have lower TBil and greater cIMT compared to controls with normal coronary angiograms.

Carotid Intima‐Media Thickness as a Novel Inflammatory Marker in Psoriasis: Comment on the Article by Lin et al

“…We found that psoriasis patients without known cardiovascular risk factors had higher arterial stiffness when compared with healthy controls in a previous study (2). CIMT is now widely used as a surrogate marker for atherosclerotic disease (3). We also demonstrated that CIMT measurement was higher in patients with psoriasis compared to the control subjects (4).…”

Neutrophil‐to‐Lymphocyte Ratio May Predict Subclinical Atherosclerosis in Patients with Psoriasis

“…2 cIMT is widely used as a surrogate marker for atherosclerotic disease based on inflammation. 4 In this context, we demonstrated that cIMT measurement is higher in patients with psoriasis compared with the control subjects. 5 So, it may be considered that increased inflammation of psoriasis contributes to atherogenesis and coronary artery disease.…”

Carotid intima media thickness can predict coronary artery disease

“…We investigated the relation between atherosclerosis and CIMT. We reported that CIMT was significantly higher in coronary artery disease(CAD) groups compared to control participants (3). We had also reported that CIMT levels were higher in newly diagnosed patients with untreated essential hypertension compared to controls(4).…”