Carotid body dysregulation contributes to Long COVID symptoms
Ahmed El-Medany,
Zoe H. Adams,
Hazel C. Blythe
et al.
Abstract:Background
The symptoms of long COVID, which include fatigue, breathlessness, dysregulated breathing, and exercise intolerance, have unknown mechanisms. These symptoms are also observed in heart failure and are partially driven by increased sensitivity of the carotid chemoreflex. As the carotid body has an abundance of ACE2 (the cell entry mechanism for SARS-CoV-2), we investigated whether carotid chemoreflex sensitivity was elevated in participants with long COVID.
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