CSF SEROTONIN IN RUPTURED ANEURYSM/ Voldby et al.
189ruptured cerebral aneurysm. J Neurol Neurosurg Psychiat 27: 198-199, 1964
2124The growing attention focused on transient ischemic attacks (TIAs) seems to have fostered an increasing disregard of the relationship between epilepsy and cerebral ischemia, and the two diagnoses have even been considered as mutually exclusive.
26Seizures in obstructions of the middle cerebral artery (MCA) have not been regarded as an outstanding feature of the clinical picture, being included among second-order symptoms.6, '• 10,12,26,27 The obvious inference is that epileptic attacks are more frequent in carotid than in MCA occlusive disease. Indeed, their actual incidence is difficult to assess on the basis of data so far available. In the carotid group, epilepsy was the presenting symptom in 6.7% of patients, whereas no MCA patient had seizures prior to the appearance of a neurological deficit. Since epileptic seizures may complicate an otherwise asymptomatic carotid obstruction, angiography should be performed whenever the other standard investigations, including CT-scan, fail to reveal the cause of a late-onset epilepsy.