Carotenoids production by Rhodosporidium paludigenum yeasts: Characterization of chemical composition, antioxidant and antimicrobial properties

Sereti, Fani; Alexandri, Maria; Papadaki, Aikaterini; Papapostolou, Harris; Kopsahelis, Nikolaos

doi:10.1016/j.jbiotec.2024.03.011

Cited by 2 publications

(1 citation statement)

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“…Among carotenoids, those with the highest industrial production comprehend astaxanthin, annatto, β -carotene, lutein, and lycopene, significant products used in dietary supplements, cosmetics, foods, and beverages [ 16 ]. Biologically, carotenoids are desirable compounds due to their ability to inhibit the growth of pathogenic Gram-positive (e.g., Staphylococcus aureus and Clostridioides difficile) and Gram-negative (e.g., Pseudomonas aeruginosa and Klebsiella oxytoca) strains [ 17 ]. Additionally, they regulate the levels of reactive oxygen species (ROS), scavenge free radicals, induce apoptosis of cancer cells, diminish the formation of new blood vessels, reduce the secretion of pro-inflammatory cytokines, and protect neurons against degradation [ 18 ].…”

Section: Introductionmentioning

confidence: 99%

Recent Advances in the Therapeutic Potential of Carotenoids in Preventing and Managing Metabolic Disorders

Ortega-Regules,

Martínez-Thomas,

Schürenkämper-Carrillo

et al. 2024

Plants

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Carotenoids constitute compounds of significant biological interest due to their multiple biological activities, such as antimicrobial, anticancer, antiadipogenic, antidiabetic, and antioxidant properties. Metabolic syndrome (MetS) comprehends a series of metabolic abnormalities (e.g., hypertension, obesity, and atherogenic dyslipidemia) that can affect children, adolescents, and the elderly. The treatment of MetS involves numerous medications, which, despite their efficacy, pose challenges due to prolonged use, high costs, and various side effects. Carotenoids and their derivatives have been proposed as alternative treatments to MetS because they reduce serum triglyceride concentrations, promote insulin response, inhibit adipogenesis, and downregulate angiotensin-converting enzyme activity. However, carotenoids are notably sensitive to pH, light exposure, and temperature. This review addresses the activity of carotenoids such as lycopene, lutein, fucoxanthin, astaxanthin, crocin, and β-carotene towards MetS. It includes a discussion of sources, extraction methods, and characterization techniques for analyzing carotenoids. Encapsulation approaches are critically reviewed as alternatives to prevent degradation and improve the biological performance of carotenoids. A brief overview of the physiopathology and epidemiology of the diseases, including MetS, is also provided.

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Section: Introductionmentioning

confidence: 99%