Carotenoids and their metabolism in the goldfish Carassius auratus (Hibuna)

Ohkubo, Masahiro; Tsushima, Miyuki; Maoka, Takashi; Matsuno, Takao

doi:10.1016/s0305-0491(99)00124-8

Cited by 30 publications

(20 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The data shows that carotenoids were derived in liver after being fed with lutein; and that fancy carp can convert lutein to astaxanthin. The results of this present study were similar to other research studies: gold fish fed with lutein and zeaxanthin diets proposed the possible metabolic pathways from lutein and zeaxanthin to astaxanthin (Ohkubo et al, 1999). This indicates that lutein is converted into -doradexanthin, leading to the formation of astaxanthin by oxidative pathway (Tanaka et al, 1976).…”

Section: Metabolized Serum Carotenoids After Administration Of Singlesupporting

confidence: 81%

Pharmacokinetics and Metabolized Caroteniods in Liver of Single Dose Administration in Fancy Carp (Cyprinus carpio)

Yuangsoi¹

2012

Readings in Advanced Pharmacokinetics - Theory, Methods and Applications

View full text Add to dashboard Cite

Section: Metabolized Serum Carotenoids After Administration Of Singlesupporting

confidence: 81%

Pharmacokinetics and Metabolized Caroteniods in Liver of Single Dose Administration in Fancy Carp (Cyprinus carpio)

Yuangsoi¹

2012

Readings in Advanced Pharmacokinetics - Theory, Methods and Applications

View full text Add to dashboard Cite

“…This carotenoid has characteristics as for alloxanthin, reported in, e.g. the goldfish Carassius auratus (Ohkubo et al. , 1999), but the identity cannot be confirmed.…”

Section: Resultsmentioning

confidence: 84%

Ornaments or offspring? Female sticklebacks (Gasterosteus aculeatus L.) trade off carotenoids between spines and eggs

Nordeide¹,

Rudolfsen

Egeland³

2006

Journal of Evolutionary Biology

View full text Add to dashboard Cite

Hypotheses and models to explain female ornaments often assume that the elaborated traits are condition dependent; nevertheless, few empirical studies have addressed this topic. We studied a population of three‐spined sticklebacks (Gasterosteus aculeatus) in which the females have conspicuous, carotenoid‐based red coloration to their pelvic spines. The red coloration seems not to be condition dependent, as coloration is negatively associated with age and body length and not associated with condition. Furthermore, redder females did not have a lower density of leucocytes. We found a negative association between the females’ red carotenoid‐based coloration in the spines and the amount of carotenoids in the female's gonads. Males choosing red‐coloured females will fertilize eggs with small amounts of carotenoids and appear not to gain any benefit from their mates’ phenotypic quality that could result in offspring of improved quality. These results do not support the ‘direct selection hypothesis’ to explain the existence of the female ornaments.

show abstract

“…fishes: Hata & Hata (1972) and Ohkubo et al (1999); birds: McGraw (2006) and references therein). This issue may be key to understanding the cost of the signal, but many obscure points are as yet not understood.…”

Section: Introductionmentioning

confidence: 99%

Specific carotenoid pigments in the diet and a bit of oxidative stress in the recipe for producing red carotenoid-based signals

Blas

Mateo

Alonso‐Álvarez

2016

PeerJ

View full text Add to dashboard Cite

Colorful ornaments have been the focus of sexual selection studies since the work of Darwin. Yellow to red coloration is often produced by carotenoid pigments. Different hypotheses have been formulated to explain the evolution of these traits as signals of individual quality. Many of these hypotheses involve the existence of a signal production cost. The carotenoids necessary for signaling can only be obtained from food. In this line, carotenoid-based signals could reveal an individual’s capacity to find sufficient dietary pigments. However, the ingested carotenoids are often yellow and became transformed by the organism to produce pigments of more intense color (red ketocarotenoids). Biotransformation should involve oxidation reactions, although the exact mechanism is poorly known. We tested the hypothesis that carotenoid biotransformation could be costly because a certain level of oxidative stress is required to correctly perform the conversion. The carotenoid-based signals could thus reveal the efficiency of the owner in successfully managing this challenge. In a bird with ketocarotenoid-based ornaments (the red-legged partridge; Alectoris rufa), the availability of different carotenoids in the diet (i.e. astaxanthin, zeaxanthin and lutein) and oxidative stress were manipulated. The carotenoid composition was analyzed and quantified in the ornaments, blood, liver and fat. A number of oxidative stress biomarkers were also measured in the same tissues. First, we found that color and pigment levels in the ornaments depended on food levels of those carotenoids used as substrates in biotransformation. Second, we found that birds exposed to mild levels of a free radical generator (diquat) developed redder bills and deposited higher amounts of ketocarotenoids (astaxanthin) in ornaments. Moreover, the same diquat-exposed birds also showed a weaker resistance to hemolysis when their erythrocytes were exposed to free radicals, with females also enduring higher oxidative damage in plasma lipids. Thus, higher color production would be linked to higher oxidative stress, supporting the biotransformation hypothesis. The recent discovery of an avian oxygenase enzyme involved in converting yellow to red carotenoids may support our results. Nonetheless, the effect could also depend on the abundance of specific substrate carotenoids in the diet. Birds fed with proportionally higher levels of zeaxanthin showed the reddest ornaments with the highest astaxanthin concentrations. Moreover, these birds tended to show the strongest diquat-mediated effect. Therefore, in the evolution of carotenoid-based sexual signals, a biotransformation cost derived from maintaining a well-adjusted redox machinery could coexist with a cost linked to carotenoid acquisition and allocation (i.e. a resource allocation trade-off).

show abstract

Carotenoids and their metabolism in the goldfish Carassius auratus (Hibuna)

Cited by 30 publications

References 17 publications

Pharmacokinetics and Metabolized Caroteniods in Liver of Single Dose Administration in Fancy Carp (Cyprinus carpio)

Pharmacokinetics and Metabolized Caroteniods in Liver of Single Dose Administration in Fancy Carp (Cyprinus carpio)

Ornaments or offspring? Female sticklebacks (Gasterosteus aculeatus L.) trade off carotenoids between spines and eggs

Specific carotenoid pigments in the diet and a bit of oxidative stress in the recipe for producing red carotenoid-based signals

Contact Info

Product

Resources

About