Cariogenic Potential of the commonly Prescribed Pediatric Liquid Medicaments in Kingdom of Saudi Arabia: An in vitro Study

Abstract

Aim:The aim of this study was to assess the cariogenic potential of the commonly prescribed pediatric liquid medicaments (PLMs) for dental disease in Jazan region, Kingdom of Saudi Arabia. Materials and methods:Seven most commonly prescribed PLMs were selected by prior questioning the pediatric dentists as well as general dentists in Jazan region. The endogenous pH and sucrose concentrations of the liquid medicaments were assessed. The endogenous pH was assessed by Hanna pH meter instrument. The sucrose concentration was assessed by anthrone reagent method.Results: All the PLM were acidic. The pH of the PLM ranged from 4.22 to 6.10. All the PLM contained sucrose and its concentration ranged from 5.38 to 11.41 gm% in the samples. Conclusion:In this study, all the PLM were acidic and contained sucrose. Hence, they have cariogenic potential.Clinical significance: Parents and dentists are unaware of the hidden sugars and cariogenicity of these medications. Strict oral hygiene instructions are mandatory for the children taking these medications. The use of PLM should also be minimized and parents should seek early dental treatment to restore child's oral health.

Evaluation of Sugar Content and Erosive Potential of the Commonly Prescribed Liquid Oral Medications

“…Many studies have been done in the US [4], Brazil [2], New Zealand [3], and Saudi Arabia [23] linking frequent use of sweetened LOM and the development of dental caries. Other authors studied the pH and concentration of sugars of pediatric liquid medicaments and suggested that these medications can pose as a threat to dental health [5,13].…”

Effect of lactoferrin on enamel characteristics of primary and permanent teeth: an in-vitro study

“…Most pediatric medicaments may contain certain acids in their liquids, which serve as a buffer to keep the solution’s chemical stability and tonicity under control and maintain physiological compatibility. They also enhance the flavor, which makes the drug more kid-friendly [ 14 ]. Since this is a pioneering study about the effect of orally supplemented lactoferrin on the enamel exterior of primary and permanent teeth, a pH meter was used to measure the pH of the lactoferrin suspension.…”