Care patterns and Traditional Chinese Medicine constitution as factors of depression and anxiety in patients with systemic sclerosis: A cross-sectional study during the COVID-19 pandemic

Kong, Qi; Chen, Liming; Dai, Zong-Hao; Tang, Yun-Zhe; Zhou, Yuyang; Tu, Wen-Zhen; Zhao, Yin-Huan; Zhang, Jiaqian

doi:10.3389/fnint.2023.1052683

Cited by 2 publications

(4 citation statements)

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“…For example, a systematic evaluation study of TCMC as a predictor of depression showed that Qi-deficiency constitution and Qi-depression constitution could be used as a predictor of depression [ 43 ]. A cross-sectional study during the COVID-19 pandemic showed that Qi-deficiency constitution and Qi-depression constitution were associated with depression and Qi-depression constitution was associated with anxiety in patients with systemic sclerosis [ 44 ]. A study of Malaysian university students also showed that Qi-depression constitution was an important risk factor for depression among university students [ 45 ].…”

Section: Discussionmentioning

confidence: 99%

Development and validation of non-invasive prediction models for migraine in Chinese adults

Duan,

Xia,

Zheng

et al. 2023

J Headache Pain

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Background Migraine is a common disabling neurological disorder with severe physical and psychological damage, but there is a lack of convenient and effective non-invasive early prediction methods. This study aimed to develop a new series of non-invasive prediction models for migraine with external validation. Methods A total of 188 and 94 subjects were included in the training and validation sets, respectively. A standardized professional questionnaire was used to collect the subjects' 9-item traditional Chinese medicine constitution (TCMC) scores, Pittsburgh Sleep Quality Index (PSQI) score, Zung's Self-rating Anxiety Scale and Self-rating Depression Scale scores. Logistic regression was used to analyze the risk predictors of migraine, and a series of prediction models for migraine were developed. Receiver operating characteristic (ROC) curve and calibration curve were used to assess the discrimination and calibration of the models. The predictive performance of the models were further validated using external datasets and subgroup analyses were conducted. Results PSQI score and Qi-depression score were significantly and positively associated with the risk of migraine, with the area of the ROC curves (AUCs) predicting migraine of 0.83 (95% CI:0.77–0.89) and 0.76 (95% CI:0.68–0.84), respectively. Eight non-invasive predictive models for migraine containing one to eight variables were developed using logistic regression, with AUCs ranging from 0.83 (95% CI: 0.77–0.89) to 0.92 (95% CI: 0.89–0.96) for the training set and from 0.76 (95% CI: 0.66–0.85) to 0.83 (95% CI: 0.75–0.91) for the validation set. Subgroup analyses showed that the AUCs of the eight prediction models for predicting migraine in the training and validation sets of different gender and age subgroups ranged from 0.80 (95% CI: 0.63–0.97) to 0.95 (95% CI: 0.91–1.00) and 0.73 (95% CI: 0.64–0.84) to 0.93 (95% CI: 0.82–1.00), respectively. Conclusions This study developed and validated a series of convenient and novel non-invasive prediction models for migraine, which have good predictive ability for migraine in Chinese adults of different genders and ages. It is of great significance for the early prevention, screening, and diagnosis of migraine.

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Section: Discussionmentioning

confidence: 99%

Development and validation of non-invasive prediction models for migraine in Chinese adults

Duan,

Xia,

Zheng

et al. 2023

J Headache Pain

View full text Add to dashboard Cite

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“…Previous studies have also shown that TCM constitution is closely related to the occurrence, development and prognosis of diseases. [7][8][9][10][11][12]22 Therefore, a balanced TCM constitution has important potential application value in preventing and alleviating clinical symptoms of COVID-19 patients and accelerating the negative nucleic acid transformation of COVID-19 patients. The time taken for COVID-19 nucleic acid conversion is related to sex, age, vaccination status, 1-3 BMI, 2 chronic diseases, 24,25 presence of sore throat symptoms, 4 high nutrition risk 26 and plasma 25(OH)D levels.…”

Section: Discussionmentioning

confidence: 99%

“…TCM constitution differences determine the susceptibility to certain diseases and the prognosis of the diseases. [7][8][9][10][11][12] Traditional Chinese medicine constitution theory believes that through diet, exercise, 28 drug conditioning and other methods can improve people's unbalanced constitution, so as to prevent the occurrence of disease, or improve the condition of patients who have been sick, and promote the recovery of disease. 29,30 Therefore, the TCM constitution has enormous potential for disease prevention and treatment applications.…”

Section: Discussionmentioning

confidence: 99%

“…[1][2][3][4][5][6] However, these indicators cannot fully reflect the general physical health status and prognosis of COVID-19 patients, while traditional Chinese medicine (TCM) constitution can reflect the general physical health status of patients and affect the occurrence, development and prognosis of the disease. [7][8][9][10][11][12] Traditional Chinese Medicine (TCM) Constitution, proposed by Wang Qi in 1978, 13 refers to the comprehensive and relatively stable inherent characteristics of the human body's morphological structure, physiological function, and psychological state formed during life processes based on both innate endowments and acquired factors. 13 It could be classified into nine types, including balanced, qi-deficient, yang-deficient, yin-deficient, Phlegm-dampness, damp-heat, stagnant blood, stagnant qi, and inherited special constitution.…”

Section: Introductionmentioning

confidence: 99%

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Impact of Different Traditional Chinese Medicine Constitutions on the Clinical Outcomes of COVID-19 Patients Infected with SARS-CoV-2 Omicron Variant: A Retrospective Observational Study

Feng,

Qiu,

Hong

et al. 2023

IDR

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Purpose Traditional Chinese Medicine (TCM) constitution and disease occurrence, development, and prognosis are interrelated. This study aimed to investigate the association between TCM constitution and the time to negative nucleic acid test results in patients with coronavirus disease 2019 (COVID-19) infected with the SARS-CoV-2 Omicron variant. Patients and Methods We identified COVID-19 patients (≥18 years) infected with the SARS-CoV-2 Omicron variant and collected clinical data, including clinical symptoms, time to negative nucleic acid test results, and TCM constitution. Linear and logistic regression analyses explored the relationship between TCM constitution and the time to negative nucleic acid test results in patients with the COVID-19 Omicron variant. Results We included 486 patients with COVID-19, with a mean age of 40.2 years; 321 (66.0%) men and 165 (34.0%) women. Balanced constitution accounted for 43.8%, and unbalanced constitution accounted for 56.2%. Chi-square test showed that different TCM constitutions had significant differences in the influence of clinical symptoms of COVID-19 patients (P < 0.01). After controlling for various factors, multiple linear regression analysis revealed that an unbalanced constitution was significantly positively correlated with time to negative nucleic acid test results (P < 0.05). After controlling for various factors, logistic regression analysis revealed that an unbalanced constitution was closely related to the 7-day nucleic acid test conversion rate (odds ratio (OR): 0.53, 95% confidence interval (CI): 0.36–0.80, P < 0.05). After dividing the unbalanced constitution into deficiency constitution and non-deficiency constitution, the non-deficiency constitution was closely associated with the 7-day nucleic acid test conversion rate (OR = 0.45, 95% CI: 0.28–0.74, P < 0.05). Further analysis revealed that damp-heat constitution in the non-deficiency constitution was associated with the 7-day nucleic acid test conversion rate (OR = 0.33, 95% CI: 0.18–0.60, P < 0.05). Conclusion In patients with COVID-19, an unbalanced constitution is associated with a longer time to negative nucleic acid test results and lower 7-day nucleic acid test conversion rates.

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Care patterns and Traditional Chinese Medicine constitution as factors of depression and anxiety in patients with systemic sclerosis: A cross-sectional study during the COVID-19 pandemic

Cited by 2 publications

References 50 publications

Development and validation of non-invasive prediction models for migraine in Chinese adults

Development and validation of non-invasive prediction models for migraine in Chinese adults

Impact of Different Traditional Chinese Medicine Constitutions on the Clinical Outcomes of COVID-19 Patients Infected with SARS-CoV-2 Omicron Variant: A Retrospective Observational Study

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