Radiologists aspire to improve patient experience and engagement, as part of the Triple Aim of health reform. Patient engagement requires active partnerships among health providers and the patient, and rigorous teamwork provides a mechanism for this. Patient and care team engagement are crucial at the time of cancer diagnosis and care initiation, but are complicated by the necessity to orchestrate many interdependent consultations and care events in a short time. Radiology often serves as the patient entry point into the cancer care system, especially in breast cancer. It is uniquely positioned to play the value-adding role of facilitating patient and team engagement during cancer care initiation. The 4R approach previously proposed for optimizing teamwork and care delivery during cancer treatment (Trosman, JOP 2016), could be applied at the time of diagnosis. The 4R approach considers care for every cancer patient as a project, using Project Management to plan and manage care interdependencies, assign clear responsibilities and designate a Quarterback function. We propose that radiology assume the Quarterback function during breast cancer care initiation, developing Care Initiation Sequence, as a project care plan for newly diagnosed patients, and engaging the patient and her care team in timely, coordinated activities. After initial consultations and treatment plan development, the Quarterback function is transitioned to surgery or medical oncology. This model provides radiologists with opportunities for value-added services and solidifying radiology’s relevance in the evolving healthcare environment. To implement 4R at cancer care initiation, it will be necessary to: change the radiology practice model to incorporate patient interaction and teamwork; develop the 4R content and local adaption approaches; and enrich radiology training with relevant clinical knowledge, patient interaction competence and teamwork skillset.