Cardiovascular risk stratification in young women: the pivotal role of pregnancy

Mattioli, Anna Vittoria; Coppi, Francesca; Bucciarelli, Valentina; Gallina, Sabina

doi:10.2459/jcm.0000000000001557

Cited by 10 publications

(5 citation statements)

References 61 publications

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“…Secondly, women often face difficulties in adopting healthy lifestyles due to the multitude of social, familial, and occupational obligations they encounter in contrast to men [16,17]. Thirdly, the adoption of healthy habits, particularly physical activity, is heavily influenced by societal, environmental, and structural factors [1][2][3]18]. It is crucial to acknowledge that the development of atherosclerosis begins early in life, emphasizing the necessity for cardiovascular primary prevention to commence at a young age in women [4,5].…”

Section: Strategies For CV Primary Prevention In Womenmentioning

confidence: 99%

“…It is crucial to acknowledge that the development of atherosclerosis begins early in life, emphasizing the necessity for cardiovascular primary prevention to commence at a young age in women [4,5]. Pregnancy presents a unique opportunity to engage young women and guide them toward preventive behaviors [1,2,7,[18][19][20].…”

Section: Strategies For CV Primary Prevention In Womenmentioning

confidence: 99%

“…Mental health conditions such as stress, anxiety, and depression can impact cardiovascular health and exacerbate risk factors for CVD. Addressing the psychological well-being of young women and implementing effective stress management strategies are essential components of comprehensive cardiovascular prevention efforts [1,[15][16][17][18].…”

Section: Strategies For CV Primary Prevention In Womenmentioning

confidence: 99%

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The Impact of Stress and Social Determinants on Diet in Cardiovascular Prevention in Young Women

Coppi,

Bucciarelli,

Solodka

et al. 2024

Nutrients

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The prevention of cardiovascular diseases is a fundamental pillar for reducing morbidity and mortality caused by non-communicable diseases. Social determinants, such as socioeconomic status, education, neighborhood, physical environment, employment, social support networks, and access to health care, play a crucial role in influencing health outcomes and health inequities within populations. Social determinants and stress in women are interconnected factors that can significantly impact women’s health and well-being. Pregnancy is a good time to engage young women and introduce them to beneficial behaviors, such as adopting essential life skills, especially diet, and learning stress management techniques. Stress influences diet, and women are more likely to engage in unhealthy eating behaviors such as emotional eating or coping with stress with food. Strong action is needed to improve women’s lifestyle starting at a young age considering that this lays the foundation for a lower cardiovascular risk in adults and the elderly. The objective of this review is to examine cardiovascular primary prevention in young healthy women, focusing particularly on unresolved issues and the influence of social determinants, as well as the correlation with stressors and their influence on diet.

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Section: Strategies For CV Primary Prevention In Womenmentioning

confidence: 99%

Section: Strategies For CV Primary Prevention In Womenmentioning

confidence: 99%

Section: Strategies For CV Primary Prevention In Womenmentioning

confidence: 99%

See 1 more Smart Citation

The Impact of Stress and Social Determinants on Diet in Cardiovascular Prevention in Young Women

Coppi,

Bucciarelli,

Solodka

et al. 2024

Nutrients

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“…Hypertension also determines a phenomenon of microvascular inflammation underlying the pathogenesis of HFpEF [21]. Interestingly, it has been suggested that there is a common pathophysiological pathway connecting preeclampsia, fetal growth retardation (FGR), and the subsequent development of heart failure with preserved ejection fraction (HFpEF) later in life [27]. This pathway involves various interconnected mechanisms.…”

Section: Hypertensionmentioning

confidence: 99%

“…Cardiovascular health before pregnancy has an impact on both adverse outcomes and future CV risk. A recent AHA statement highlighted that it is essential to assess cardiovascular health in young women and promote primary prevention by following the "8 essential" guidelines [27,68]. The "8 essential" framework includes eight key health factors: diet, physical activity, no smoking, body mass index, blood pressure, lipids, sleep health, and blood sugar.…”

Section: Sex-specific Risk Factors In Womenmentioning

confidence: 99%

Risk Factors and Cellular Differences in Heart Failure: The Key Role of Sex Hormones

Delcuratolo,

Palazzuoli,

Coppi

et al. 2023

Biomedicines

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Patients with heart failure are conventionally stratified into phenotypic groups based on their ejection fraction. The aim of this stratification is to improve disease management with a more targeted therapeutic approach. A further subdivision based on patient gender is justified. It is recognized that women are underrepresented in randomized controlled clinical trials, resulting in limited clinical and molecular differentiation between males and females. However, many observational studies show that the onset, development, and clinical course of the disease may substantially differ between the two sexes. According to the emerging concept of precision medicine, investigators should further explore the mechanisms responsible for the onset of heart failure due to sex differences. Indeed, the synergistic or opposing effects of sex hormones on the cardiovascular system and underlying heart failure mechanisms have not yet been clarified. Sex hormones, risk factors impact, and cardiovascular adaptations may be relevant for a better understanding of the intrinsic pathophysiological mechanisms in the two sexes. Despite the differences, treatment for HF is similar across the whole population, regardless of sex and gender. In our review, we describe the main differences in terms of cardiovascular dysfunction, risk factors, and cellular signaling modifications related to the hormonal pattern.

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Teaching gender medicine can enhance the quality of healthcare

Mattioli,

Bucciarelli,

Gallina

2024

American Heart Journal Plus: Cardiology Research and Practice

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Cardiovascular risk stratification in young women: the pivotal role of pregnancy

Cited by 10 publications

References 61 publications

The Impact of Stress and Social Determinants on Diet in Cardiovascular Prevention in Young Women

The Impact of Stress and Social Determinants on Diet in Cardiovascular Prevention in Young Women

Risk Factors and Cellular Differences in Heart Failure: The Key Role of Sex Hormones

Teaching gender medicine can enhance the quality of healthcare

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