Cardiovascular risk factors in males with hypertriglycemic waist (Tehran Lipid and Glucose Study)

Abstract

BACKGROUND: Many studies performed on nontraditional risk factors have proposed a metabolic triad including increased serum level of apolipoprotein B, hyperinsulinemia and high small, dense LDL-C as a risk factor of cardiovascular diseases. Hypertriglycemic waist (increased waist circumference as well as high fasting triglyceride level) can be used as a simple criterion to predict the metabolic triad. The aim of this study was to investigate the prevalence of hypertriglycemic waist and the frequency of cardiovascular risk factors in the affected population. MATERIALS AND METHODS:The study was performed on 4169, 18-70 y-old male subjects of the population of Tehran Lipid and Glucose Study (TLGS). The subjects fell into four groups with respect to serum level of fasting triglycerides (Tg) and waist circumference (WC). Subjects of group 1 had serum Tg Z1.8 mmol/l as well as WC Z95 cm, while those of group 2 had Tg Z1.8 mmol/l and WC o95 cm. The triglycerides level was less than 1.8 mmol/l in groups 3 and 4, whereas WC was Z95 cm and lower than 95 cm, respectively. Cardiovascular risk factors, anthropometric and laboratory variables were compared between the groups. RESULTS: In total, 784 subjects had high serum levels of Tg as well as increased WC. The mean age of subjects was significantly higher in groups 1 and 3 compared to others (37715, 48714, 41 þ 13 and 46713 y of age in groups 4, 3, 2 and 1, respectively, Po0.001). The prevalence of cardiovascular risk factors was significantly higher in group 1 as compared with others. Systolic and diastolic blood pressure, body mass index and WC were significantly higher in group 1 than in the others. Serum total cholesterol, Tg and LDL-C were significantly higher in group 1 compared to others, whereas HDL-C was significantly lower in this group. The prevalence of subjects who had at least four risk factors was 75 and 8% in groups 1 and 4, respectively. CONCLUSION: Hypertriglycemic waist can be used as a simple criterion to predict cardiovascular risk factors.

Associação entre obesidade central, triglicerídeos e hipertensão arterial em uma área rural do Brasil

“…High levels of serum TG have been observed in subjects presenting abdominal obesity 21 , and some authors have referred to the occurrence of these two factors as hypertriglyceridemic waist. There is a considerable body of evidence to indicate a strong association between hypertriglyceridemic waist and the risk of cardiovascular diseases 21,[22][23][24] .…”

Estudio de correlación entre los diagnósticos de cintura hipertrigliceridémica y síndrome metabólico en adultos de Trujillo, Perú

“…En el presente estudio, la frecuencia de CHTG según Gómez, en el total de la población estudiada, fue de 30% en 500 individuos de Trujillo de 20 a 79 años, mayor a lo reportado por el mismo Gómez que fue de 14,5 % en 2 270 individuos de España de 18 a 80 años; así mismo, la frecuencia en varones fue de 29,71 % y en mujeres de 30,3%; a diferencia de lo encontrado por Gómez que fue mayor en varones (18,2%) que en mujeres (10,8%); además, se encontró el incremento con la edad, siendo mayor en varones de 60 a 79 años y en mujeres de 40 a 59 años, muy semejante a lo reportado por Gómez (8,17) . La mayor frecuencia en varones y el incremento con la edad ha sido reportada por otros autores (25,26) .…”

Anthropometry in cardio-metabolic risk assessment

“…Već se skoro desetljeće razmatra i ispituje i varijabilnost unutar skupine osoba s povećanim OT-om s obzirom na rizik od razvoja metaboličkog sindroma, koronarne bolesti srca i dijabetesa tipa 2 (29,(41)(42)(43)(44).…”