Cardiovascular risk factors in a Roma sample population from Romania

Weiss, Emma; Japie, C.; Balahura, Ana Maria; Bartos, D.; Bădilă, Elisabeta

doi:10.2478/rjim-2018-0010

Cited by 22 publications

(32 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Consequently, the Roma people were less employed. All these variables have been previously reported by others [ 23 ]. Physical activity and imprisonment was more frequent among the Roma.…”

Section: Discussionmentioning

confidence: 87%

Serum Uric Acid in Roma and Non-Roma—Its Correlation with Metabolic Syndrome and Other Variables

Petríková

Janíčko

Fedačko

et al. 2018

IJERPH

View full text Add to dashboard Cite

Background: The Roma population is one of the major marginalized groups in Europe, having higher incidence of all spectrums of disease and a shorter life expectancy. Yet, the reasons for higher morbidity and its exact prevalence were not properly studied. Objectives: The objective of our study was to compare the frequency of metabolic syndrome (MetS) in Roma people to the non-Roma population in Slovakia, and to compare levels of uric acid and its correlation with components of metabolic syndrome. Methods: A group of 452 Roma people aged 18–55 years, was compared to a control group of 403 non-Roma people. The data were obtained by questionnaire, anthropometric measures, and analyzed blood and urine samples Results: The prevalence of MetS was significantly higher among Roma participants (131; 29.6%) compared with non-Roma participants (80; 20.1%), p = 0.001. Roma people significantly more often fulfilled obesity and low high-density lipoprotein (HDL) criteria of MetS (257, 58.9% vs. 180, 45.8%, p < 0.0001, and 312, 70.0% vs. 140, 34.9%, p < 0.0001). There was no difference in the triacylglycerols (TG), glycemia or blood pressure (BP) criteria of MetS. The Roma also presented with greater levels of high sensitivity C-reactive protein (hs-CRP). Baseline levels of uric acid (UA) among the Roma population were significantly lower compared with the majority population (226.54 ± 79.8 vs. 259.11 ± 84.53) (p < 0.001). The levels of UA significantly correlated with fulfilled criteria of MetS. Univariate regression showed that UA is a significant predictor of MetS in the whole cohort (unadjusted odds ratio (OR) 1.005; 95% CI 1.004–1.007; p < 0.0001) also after the adjustment for age, sex, and ethnicity (adjusted OR 1.008; 95% CI 1.005–1.010; p < 0.0001). Conclusions: We were able to show that prevalence of MetS among the Roma is higher than in the majority population. Moreover, the uric acid levels are significantly lower in the Roma group as well as when it comes to a cohort with MetS. Levels of UA, besides others, depend on ethnicity, age, and sex.

show abstract

“…Consequently, the Roma people were less employed. All these variables have been previously reported by others [ 23 ]. Physical activity and imprisonment was more frequent among the Roma.…”

Section: Discussionmentioning

confidence: 87%

Serum Uric Acid in Roma and Non-Roma—Its Correlation with Metabolic Syndrome and Other Variables

Petríková

Janíčko

Fedačko

et al. 2018

IJERPH

View full text Add to dashboard Cite

show abstract

“…Various studies were conducted to define the prevalence of cardiovascular risk factors among Roma and it was found to be highly increased among them [9][10][11][12]. The elevated TG/HDL-C ratio is one of the most important risk predictors with a high heritability background [24], and it combines the risk represented by reduced HDL-C and elevated TG levels, which are predictors of the early onset of cardiovascular diseases [20,21].…”

Section: Discussionmentioning

confidence: 99%

“…A number of studies have investigated the prevalence of risk factors of CVDs (e.g., obesity, hypertension, smoking, lipids and lipoprotein profile, etc.) among Roma and found it to be higher than in the general population [9][10][11][12]. Comparative studies on the risk profile for Roma adults indicate that the Roma population has significantly lower high-density lipoprotein cholesterol (HDL-C) levels, as well as no or slightly elevated TG levels in comparison to the majority population, irrespective of the country where they live [13][14][15].…”

Section: Introductionmentioning

confidence: 99%

The Effect of Haplotypes in the CETP and LIPC Genes on the Triglycerides to HDL-C Ratio and Its Components in the Roma and Hungarian General Populations

Pikó

Fiatal

Werissa

et al. 2020

Genes

View full text Add to dashboard Cite

Background: The triglycerides (TG) to high-density lipoprotein (HDL)-cholesterol (HDL-C) ratio (TG/HDL-C) is a well-known predictor for cardiovascular diseases (CVDs) with great heritability background. The cholesteryl ester transfer protein (CETP) and hepatic lipase (LIPC) gene affect TG/HDL-C ratio. This study aims to explore the association between haplotypes (H) in CETP (based on 5 single nucleotide polymorphisms (SNPs)) and LIPC (based on 6 SNPs) genes and the TG/HDL-C ratio and its components, among Roma and Hungarian general populations. Methods: The prevalence of haplotypes and their effect on HDL-C, TG and TG/HDL-C ratio were calculated in both populations and compared. Results: Ten haplotypes in CETP and 6 in LIPC gene were identified. Three haplotypes in CETP and 3 in LIPC have significant effect on HDL-C level, whereas two in CETP and 3 in LIPC on TG level. The H6 in CETP (β = 0.52, p = 0.015; odds ratio (OR) = 1.87, p = 0.009) and H5 in LIPC (β = 0.56, p < 0.001; OR = 1.51, p = 0.002) have a significant increasing effect on TG/HDL-C ratio and have shown higher prevalence among the Roma, as compared to Hungarian general population. The H2 in the CETP gene has a decreasing effect on the TG/HDL-C ratio (OR = 0.58, p = 0.019) and is significantly less frequent among the Roma. Conclusions: Accumulation of harmful haplotypes in CETP and LIPC genes might have a role in the elevated TG/HDL-C ratio in the Roma population, which contributes to a higher risk in the development of cardiovascular diseases.

show abstract

“…Roma life expectancy is shorter, and infant mortality rates are higher in Roma (6). The Roma population often face frequent health problems, including a higher prevalence of tuberculosis, cardiovascular diseases, and other communicable and noncommunicable diseases (7,8).…”

Section: Introductionmentioning

confidence: 99%

Unmet Health Needs of Roma Women in the Two Biggest Roma Communities in the Republic of Srpska, Bosnia and Herzegovina

Stojisavljevic

Grabež

Stojanovski

2020

Front. Public Health

View full text Add to dashboard Cite

Background: Reasons for unmet health needs vary from individual to contextual determinants but are defined as the difference between needed health service and services actually received. Roma experience elevated health issues and challenging social conditions. Objective: The aim of this study was to explore the unmet health needs and potential risk factors among Roma women living in the two biggest Roma communities in the Republic of Srpska. Method: We conducted a health assessment of 183 adult Roma women in the Republic of Srpska. Unmet health needs were observed as the absence of needed medical supervision, despite having chronic conditions. We used logistic regression to assess the degree to which unmet health needs were related to the social determinants and the health status of Roma women. Results: The majority of Roma women were married or were in an unofficial relationship (55.2%), were without schooling (62.8%), and were unemployed (88.5%). The results showed that 94.0% had health insurance, had a health card, and were registered with a family medicine doctor. Sixty percent reported having a chronic disease; however, 68.2% reported that their chronic disease was not medically supervised. Roma women that had less education, those who were unemployed, and those who were divorced or widowed women were more likely to have unmet health needs. Conclusion: Roma women in Bijeljina and Prijedor have unmet health needs due to the circumstances they live in despite the fact that majority of them have health insurance and universal health access is legally guaranteed.

show abstract

Cardiovascular risk factors in a Roma sample population from Romania

Abstract: The study shows that the Roma population in a more affluent region in Romania shares a similarly high cardiovascular burden to their surrounding community.

Cited by 22 publications

References 29 publications

Serum Uric Acid in Roma and Non-Roma—Its Correlation with Metabolic Syndrome and Other Variables

Serum Uric Acid in Roma and Non-Roma—Its Correlation with Metabolic Syndrome and Other Variables

The Effect of Haplotypes in the CETP and LIPC Genes on the Triglycerides to HDL-C Ratio and Its Components in the Roma and Hungarian General Populations

Unmet Health Needs of Roma Women in the Two Biggest Roma Communities in the Republic of Srpska, Bosnia and Herzegovina

Contact Info

Product

Resources

About