Cardiovascular Risk Factors and Venous Thromboembolism Incidence

Abstract

Our data showing no relationship of some arterial risk factors with VTE corroborate the view that the etiology of VTE differs from atherosclerotic cardiovascular disease. In addition, the findings suggest a hypothesis that avoidance of obesity and diabetes or vigilance in prophylaxis in patients with those conditions may prevent some venous thromboses.

Comparison of characteristics from White‐ and Black‐Americans with venous thromboembolism: A cross‐sectional study

“…Although we found other potential VTE risk factors such as sickle cell trait and disease, [24] HIV-infection [25], and anticardiolipin antibodies [26] to be higher among Blacks when compared with Whites, the prevalence of these disorders among Blacks was low and insufficient to account for the reported higher VTE incidence among Blacks [5,[8][9][10]. Blacks had a higher BMI and a higher prevalence of hypertension, diabetes mellitus, and chronic renal disease (including hemodialysis), but the association of these characteristics with VTE is uncertain [3,5,27].…”

“…However, when compared with Whites, Black-Americans appear to have a higher risk for [5,6] and incidence of VTE [7][8][9][10]. Two single-nucleotide polymorphisms, factor V Leiden (G1691A) and prothrombin G20210A, have been identified as risk factors for deep vein thrombosis (DVT) and pulmonary embolism (PE) in Europeans and White-Americans, [11][12][13][14][15][16] but not Black-Americans [6,17,18].…”

Thromboembolism Prophylaxis in End‐Stage Renal Disease

“…27 One view is that venous and arterial thromboses are unrelated. 28 However, in contrast, supporting a relationship between venous and arterial events, there are shared risk factors: both are prothrombotic states, and atherosclerosis may induce VTE (platelet activation, blood coagulation, and increase in fi brin turnover). 29 Patients with spontaneous VTE (no identifi able acquired or inherited risk factor) have a higher prevalence of asymptomatic carotid plaques than controls or patients with secondary thrombosis, suggesting oe 31 Evidence indicates a relationship between venous and arterial events; further research is needed to determine which comes fi rst.…”

Rheumatoid arthritis and venous thromboembolic events

“…Появились данные о том, что прием НПВП ассоции-руется не только с артериальными, но и с венозными тром-бозами [45][46][47]. В исследование S. Biere-Rafi и соавт.…”

“…Tsai и соавт. [47], прием НПВП повышает риск ВТЭО в 1,44 раза, однако эти результаты были аннулированы после поправки на такие ФР, как индекс массы тела и сахарный диабет. K. Lacut и соавт.…”