Cardiovascular mortality and water quality.

Abstract

Our trial has shown (after 200 patients) a decrease in infarct size (approximately onethird) and a reduction in the numbers developing complete infarction in those patients given intravenous beta-blockers within 12 hours of the onset of pain.' The treated group needed less diuretics both in hospital and on discharge, suggesting clinical as well as biochemical and electrophysiological benefit. It is important, as Professor Rose points out, not to dismiss (with small trials) therapy which might reduce morbidity and perhaps mortality by, say, 20% as being clinically insignificant in this common condition.