Cardiovascular Magnetic Resonance in Endocardial Fibroelastosis

Raman, Subha V.; Mehta, Rohit; Walker, Jon; Pennell, Dudley J.

doi:10.1081/jcmr-200053548

Cited by 12 publications

(5 citation statements)

References 7 publications

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“…However, with the development of magnetic resonance imaging (MRI) and the use of electrocardiography and respiratory gating, cardiac MRI can play a more important role in diagnosing EFE. Patients suspected of having EFE should be recommended to receive a CMR for diagnosis and a comprehensive evaluation of their cardiac function ( 20 , 21 ).…”

Section: Discussionmentioning

confidence: 99%

The value of cardiac magnetic resonance imaging in endocardial fibroelastosis

Xiao

Wang²,

Cheng³

et al. 2022

Front. Pediatr.

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IntroductionEndocardial fibroelastosis (EFE), an uncommon congenital heart disorder often occurring in infants, has a poor prognosis. It is of great significance to perform early diagnosis and accurately analyze cardiac function to enable further clinical treatment and prognosis decisions. This study aimed to explore the findings of cardiac magnetic resonance (CMR) in patients with EFE, including morphological changes and cardiac function analyses. Additionally, we compared the difference in the evaluation of the cardiac function between CMR and echocardiography (Echo).MethodsEleven patients with EFE (nine females and two males, aged between 0.3 and 1.9 years), treated in our hospital, were analyzed retrospectively. Left ventricular posterior wall thickness (LVPW), anterior wall thickness (LVAW), fractional shortening (FS), ejection fraction (EF), end-systolic diameter (ESD), end-diastolic diameter (EDD), end-systolic volume (ESV), and end-diastolic volume (EDV) were assessed using both Echo and CMR. The Original Ross classification and the New York Heart Association functional classification were used to grade the patients’ cardiac function. The correlations between clinical cardiac function classification and MRI- and Echo-derived imaging data were determined.ResultsAll patients showed a thickened endocardium and left ventricle globular dilatation on CMR. We observed significant systolic dysfunction and whole or segmental abnormal ventricular movement. Compared with those measured by Echo, the EF, FS, and EDV values were significantly lower when measured using CMR. Compared with Echo measurements, the ESV, ESD, LVAW, and LVPW values were significantly higher when measured using CMR. CMR-measured EF and FS correlated better with the clinical cardiac functional score than those derived from Echo (EF, r = 0.646 > 0.224; FS, r = 0.627 > 0.245, respectively).ConclusionIn patients with EFE, the characteristic morphological changes of the heart could be displayed accurately using CMR. The parameters measured by CMR were more accurate than those of Echo and correlated well with clinical cardiac function scores, mainly because it does not make invalid geometrical assumptions.

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Section: Discussionmentioning

confidence: 99%

The value of cardiac magnetic resonance imaging in endocardial fibroelastosis

Xiao

Wang²,

Cheng³

et al. 2022

Front. Pediatr.

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“…Although tissue diagnosis is the only means for a definitive diagnosis, characteristic imaging findings have been described in the literature that can increase the suspicion for EMF, including late and/or delayed enhancement of endothelium as characteristic findings in patients with EMF 8 , 9 , 10 . The tissue deposited in EMF has increased extracellular volume, and thus appears brighter on delayed enhancement imaging because the more vascularized regions wash out the contrast, resulting in the “V pattern” of delayed enhancement (8) .…”

Section: Discussionmentioning

confidence: 99%

Isolated Right-Sided Endomyocardial Fibroelastosis Resulting in Sudden Cardiac Death

Chaudhry

Ashwath

2019

JACC: Case Reports

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“…However, there is a weak association between the echocardiographic appearance of echo-brightness of the myocardium and histologic evidence of EFE at autopsy [2]. Recent reports have described the utility of myocardial delayed-enhancement MRI in establishing the diagnosis of EFE [3,4]. We describe here our experience with MRI in establishing the presence of EFE in three children.…”

Section: Introductionmentioning

confidence: 87%