Cardiovascular impact of eating disorders in adults: A single center experience and literature review

Sardar, Muhammad; Greway, Andrea; DeAngelis, Michael; Tysko, Erin O’Malley; Lehmann, Shawn; Wohlstetter, Melinda; Patel, Riti

doi:10.4103/1995-705x.164463

Cited by 17 publications

(19 citation statements)

References 26 publications

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“…The main cardiovascular complications in patients with AN are bradycardia, systolic dysfunction, impaired ventricular repolarization, low blood pressure, QT interval prolongation, mitral valve prolapse, and reduction of myocardial contractility [1, 2]. The mechanistic pathways linking AN to left ventricular systolic function decline are not clear.…”

Section: Discussionmentioning

confidence: 99%

“…Moreover, malnutrition alters the blood concentration of various hormones (e.g., insulin, thyroid hormones, glucocorticoids, and growth hormones). As a result, the myocardium at the cellular level might suffer from diminished protein synthesis, decreased cardiac mass, and changes in myocardial contractility [2]. Consequently, depletion of intramyocardial glycogen and myocardium atrophy could cause a decrease in vagal tone, bradycardia, and QT interval prolongation.…”

Section: Discussionmentioning

confidence: 99%

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An Endomyocardial Biopsy of the Left Ventricle in an Anorexia Nervosa Patient with Sinus Bradycardia and Left Ventricular Systolic Dysfunction

Takahashi

Mine

2016

Case Reports in Cardiology

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Anorexia nervosa (AN) is an eating disorder characterized by an abnormally low body weight, an intense fear of gaining weight, and a distorted perception of body weight. AN is a life-threatening condition that significantly increases the risk of death due to cardiac complications, such that at least one-third of all deaths in patients with AN are associated with cardiac causes including sudden death. In many reports, sudden death has been linked to reduced left ventricular function, structural changes, and QT abnormalities. However, the mechanistic details connecting AN to cardiac abnormalities remain unknown. Here we present an endomyocardial biopsy of the left ventricle in a case of AN with a reversible left ventricular systolic dysfunction.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

An Endomyocardial Biopsy of the Left Ventricle in an Anorexia Nervosa Patient with Sinus Bradycardia and Left Ventricular Systolic Dysfunction

Takahashi

Mine

2016

Case Reports in Cardiology

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“…In addition, some cancer patients experience depression and pain, further decreasing the desire to eat [ 17 ]. Eating disorders have multiple medical consequences, such as potentially life-threatening cardiovascular complications characterized by hemodynamic and structural changes, cardiomyopathy, and premature death [ 18 ].…”

Section: Cardio-oncology Syndrome Type I (Cos 1; Direct): Effect Of the Presence Of Cancer Itself On The Cardiovascular Systemmentioning

confidence: 99%

A new classification of cardio-oncology syndromes

et al. 2021

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Increasing evidence suggests a multifaceted relationship exists between cancer and cardiovascular disease (CVD). Here, we introduce a 5-tier classification system to categorize cardio-oncology syndromes (COS) that represent the aspects of the relationship between cancer and CVD. COS Type I is characterized by mechanisms whereby the abrupt onset or progression of cancer can lead to cardiovascular dysfunction. COS Type II includes the mechanisms by which cancer therapies can result in acute or chronic CVD. COS Type III is characterized by the pro-oncogenic environment created by the release of cardiokines and high oxidative stress in patients with cardiovascular dysfunction. COS Type IV is comprised of CVD therapies and diagnostic procedures which have been associated with promoting or unmasking cancer. COS Type V is characterized by factors causing systemic and genetic predisposition to both CVD and cancer. The development of this framework may allow for an increased facilitation of cancer care while optimizing cardiovascular health through focused treatment targeting the COS type.

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“…Besides psychological and social consequences of ED, these patients usually carry also a burden of physical aftermath of their mental disturbances (i.e., malnutrition, obesity, changes of weight, dysregulated endocrine, reproductive and skeletal systems, micronutrients deficiencies, hemodynamic changes, cardiomyopathy, arrhythmia, hypotension, and bradycardia [20][21][22][23]). That makes them hypothetically more vulnerable to after-effects of COVID-19 [24].…”

Section: Impact Of Ed On Covid-19mentioning

confidence: 99%

Is the Pandemic a Risk Factor for Eating Disorders?

Dąbkowska-Mika¹

2021

Anxiety, Uncertainty, and Resilience During the Pandemic Period - Anthropological and Psychological Perspectives

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COVID-19 has already established direct or indirect effect on the lives of everyone. One of its many consequences is exacerbation of eating disorders´ (ED) triggers. Numerous risk factors for ED are enhanced during pandemic – anxiety, fear, depressed mood. Distance learning or working may result in loss of daily-life routine and feeling of being overwhelmed with duties. Due to forced isolation people are more exposed to social media pressure. Additionally, awareness of limitations of physical activity can develop fear of gaining the weight. These are typical symptoms of Anorexia Nervosa, a disease with the highest mortality rate among psychiatric disorders. Frustration, tedium and lack of external distractors can lead to inappropriate food-related coping style. Especially during the first wave of the pandemic, society was cautious about fresh food supplies and therefore many decided to stock up with processed, unhealthy food. Aggregation of stressors (e.g., worries about health, financial problems, loneliness) may promote binge eating.

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Cardiovascular impact of eating disorders in adults: A single center experience and literature review

Cited by 17 publications

References 26 publications

An Endomyocardial Biopsy of the Left Ventricle in an Anorexia Nervosa Patient with Sinus Bradycardia and Left Ventricular Systolic Dysfunction

An Endomyocardial Biopsy of the Left Ventricle in an Anorexia Nervosa Patient with Sinus Bradycardia and Left Ventricular Systolic Dysfunction

A new classification of cardio-oncology syndromes

Is the Pandemic a Risk Factor for Eating Disorders?

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