Cardiovascular effects of increasing dosages of norepinephrine in healthy isoflurane-anesthetized New Zealand White rabbits

Cardiovascular effects of dobutamine, norepinephrine and phenylephrine in isoflurane-anaesthetized dogs administered dexmedetomidine–vatinoxan

“…The half-life of norepinephrine is short, approximately 2 minutes (Beloeil et al 2005). The norepinephrine infusion dosages required in the present study to achieve and maintain normotension were comparable with the dosages published in foals, alpacas and rabbits to treat isofluraneinduced hypotension (Valverde et al 2006;Vincent et al 2009;Uccello et al 2020). In the present study, the administration of norepinephrine infusion significantly improved blood pressure (SAP and MAP) through enhanced SVI and CI.…”