Cardiovascular disease: Mitochondrial dynamics and mitophagy crosstalk mechanisms with novel programmed cell death and macrophage polarisation

Liu, Dandan; Qin, Hewei; Gao, Yang; Sun, Mengyan; Wang, Mengnan

doi:10.1016/j.phrs.2024.107258

Pharmacological Research

2024

DOI: 10.1016/j.phrs.2024.107258

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Cardiovascular disease: Mitochondrial dynamics and mitophagy crosstalk mechanisms with novel programmed cell death and macrophage polarisation

Dandan Liu,

Hewei Qin,

Yang Gao

et al.

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2024

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Cited by 2 publications

References 164 publications

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Novel Compounds as NLRP3 Inhibitors for Treating Cardiovascular Diseases

Sabnis

2024

ACS Med. Chem. Lett.

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Novel Compounds as NLRP3 Inhibitors for Treating Cardiovascular Diseases

Sabnis

2024

ACS Med. Chem. Lett.

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The Role of Endothelial Cell Mitophagy in Age-Related Cardiovascular Diseases

Han,

Yu,

Liu

et al. 2024

Aging and disease

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Aging is a major risk factor for cardiovascular diseases (CVD), and mitochondrial autophagy impairment is considered a significant physiological change associated with aging. Endothelial cells play a crucial role in maintaining vascular homeostasis and function, participating in various physiological processes such as regulating vascular tone, coagulation, angiogenesis, and inflammatory responses. As aging progresses, mitochondrial autophagy impairment in endothelial cells worsens, leading to the development of numerous cardiovascular diseases. Therefore, regulating mitochondrial autophagy in endothelial cells is vital for preventing and treating age-related cardiovascular diseases. However, there is currently a lack of systematic reviews in this area. To address this gap, we have written this review to provide new research and therapeutic strategies for managing aging and age-related cardiovascular diseases.

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Cardiovascular disease: Mitochondrial dynamics and mitophagy crosstalk mechanisms with novel programmed cell death and macrophage polarisation

Cited by 2 publications

References 164 publications

Novel Compounds as NLRP3 Inhibitors for Treating Cardiovascular Diseases

Novel Compounds as NLRP3 Inhibitors for Treating Cardiovascular Diseases

The Role of Endothelial Cell Mitophagy in Age-Related Cardiovascular Diseases

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