Cardiovascular disease in children in Djibouti: a single-centre study

Massoure, Pierre‐Laurent; Roche, Nicolas-Charles; Lamblin, G.; Dehan, Céline; Kaiser, É.; Fourcade, Laurent

doi:10.11604/pamj.2013.14.141.2016

Cited by 10 publications

(9 citation statements)

References 9 publications

(14 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Studies suggest that treated cases of pulmonary stenosis may experience operative mortality of 3–6% and a postoperative mortality of 4–5% by 25 years after surgery . Cardiac defects that require surgery but remain untreated increase mortality risks and decrease life expectancy . We assume the technology from older studies approximates the current technology in minimal treatment settings today.…”

Section: Resultsmentioning

confidence: 99%

Systematic Review of the Manifestations of Congenital Rubella Syndrome in Infants and Characterization of Disability‐Adjusted Life Years (DALYs)

et al. 2014

View full text Add to dashboard Cite

Congenital rubella syndrome (CRS) continues to cause disability among unvaccinated populations in countries with no or insufficient rubella vaccine coverage to prevent transmission. We systematically reviewed the literature on birth outcomes associated with CRS to estimate the duration, severity, and frequency of combinations of morbidities. We searched PubMed, the Science Citation Index, and references from relevant articles for studies in English with primary data on the frequency of CRS manifestations for ≥20 cases and identified 65 studies representing 66 study populations that met our inclusion criteria. We abstracted available data on CRS cases with one or more hearing, heart, and/or eye defect following maternal rubella infection during the period of 0-20 weeks since the last menstrual period. We assessed the quality and weight of the available evidence using a modified Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. Most of the evidence originates from studies in developed countries of cohorts of infants identified with CRS in the 1960s and 1970s, prior to the development of standardized definitions for CRS and widespread use of vaccine. We developed estimates of undiscounted disability-adjusted life years (DALYs) lost per CRS case for countries of different income levels. The estimates ranged from approximately 19 to 39 for high-income countries assuming optimal treatment and from approximately 29 to 39 DALYs lost per CRS case in low- and lower- middle-income countries assuming minimal treatment, with the lower bound based on 2010 general global burden of disease disability weights and the upper bound based on 1990 age-specific and treatment-specific global burden of disease disability weights. Policymakers and analysts should appreciate the significant burden of disability caused by CRS as they evaluate opportunities to manage rubella.

show abstract

Section: Resultsmentioning

confidence: 99%

Systematic Review of the Manifestations of Congenital Rubella Syndrome in Infants and Characterization of Disability‐Adjusted Life Years (DALYs)

et al. 2014

View full text Add to dashboard Cite

show abstract

“…As demonstrated around the world [6,[8][9][10][11][12], VSDs were the commonest forms of CHD diagnosed in Northern Uganda. The peculiar nding in this study was the high number of cases of AVSD seen, accounting for 17.1%, whereas most studies from Africa report prevalence of AVSD between 5-8% of total CHD [9,11].…”

Section: Discussionmentioning

confidence: 99%

Profile of Congenital Heart Disease and Access to Definitive Care Among Children Seen at Gulu Regional Referral Hospital in Northern Uganda: a Four-year Experience

Aliku

Beaton

Lubega

et al. 2020

Preprint

View full text Add to dashboard Cite

Objectives: The aim of this study was to describe the profile of Congenital Heart Disease [CHD] and access to definitive surgical or catheter-based care among children attending a regional referral hospital in Northern Uganda. Methods: This was a retrospective chart review of all children aged less than 17 years attending Gulu Regional Referral Hospital Cardiac clinic from November 2013 to July 2017. Results: A total of 299 children were diagnosed with CHD during the period. The median age at diagnosis was 12 months ([QR: 4 – 48] with females representing 59.2% [n=177] of cases. Neonates comprised only 7.4% [n=22]. The commonest CHD seen was ventricular septal defect [VSD] in 19.4% [n=58] of cases, followed by atrioventricular septal defect (AVSD) in 17.1% [n=51] and patent ductus arteriosus (PDA) in 15.7% [n=47]. The commonest cyanotic CHD seen was tetralogy of Fallot [TOF] in 5% [n=15], followed by double outlet right ventricle [DORV] in 4% [n=12] and truncus arteriosus in 3.4% [n=10]. Dextro-transposition of the great arteries [D-TGA] was seen in 1.3% [n=4]. At initial evaluation, 75% [n=224] of all CHD needed definitive intervention and 14% of these children [n=32] had accessed surgical or catheter-based therapy within 2 years of diagnosis. Three quarters of the cases who had intervention [n=24] had definitive care at the UHI including all 12 cases who underwent catheter-based interventions. Conclusions: There is delayed diagnosis of most rural Ugandan Children with CHD and access to definitive care is severely limited. In-country programs offer the most feasible option to increase access to definitive care.

show abstract

Section: Resultsmentioning

confidence: 99%

“…A total of 18 studies were included in this systematic review and meta-analyses, encompassing 9109 patients [ 10 – 19 , 22 – 27 , 30 , 31 ]. Of them 8 studies were done in Ethiopia [ 11 – 17 , 30 ], 2 in Kenya [ 18 , 19 ], while 3 were in Sudan [ 22 , 23 , 31 ], 1 in Djibouti [ 10 ], 1 in Uganda [ 27 ], and 3 in Tanzania [ 24 – 26 ]. Based on the study design used 15 studies were done by cross-sectional study design [ 11 – 17 , 19 , 22 – 25 , 27 , 30 , 31 ] and other 3 studies were conducted by cohort study design [ 10 , 18 , 26 ].…”

Section: Resultsmentioning

confidence: 99%

Prevalence of congenital septal defects among congenital heart defect patients in East Africa: A systematic review and meta-analysis

2021

View full text Add to dashboard Cite

Introduction Congenital heart defects (CHDs) are the most common congenital defects and accounts for nearly one-third of all major congenital anomalies. It is the leading causes of birth defect-associated morbidity, mortality, and medical expenditures. Of all CHD types, ventricular septal defect (VSD) and atrial septal defect (ASD) accounted 51% of cases with an increasing trend over time. Objective The aim of this review is to estimate the pooled prevalence of ventricular septal defect and congenital atrial septal defect among congenital heart diseases patients in East African context. Methods Using PRISMA guideline, we systematically reviewed and meta-analyzed studies that examined the prevalence of Ventricular septal defect and atrial septal defect in East Africa, from Medline (PubMed), Cochrane Library, HINARI, and Google Scholar. A weighted inverse variance random-effects model was used to estimate the pooled prevalence of ventricular septal defect and atrial septal defect. Results A total of 2323 studies were identified; 1301 from PubMed, 12 from Cochrane Library, 1010 from Google Scholar and 22 from other sources. The pooled prevalence of ventricular septal defect and atrial septal defect in East Africa was found to be 29.92% (95% CI; 26.12–33.72; I2 = 89.2%; p<0.001), and 10.36% (95% CI; 8.05–12.68; I2 = 89.5%; p<0.001) respectively. Conclusions and future implications Based on this review, the pooled prevalence of VSD and ASD is still high and alarming; this signifies that the emphasis given for congenital heart defect in East African countries is limited. Special attention and efforts should be applied for early detection to prevent serious complications and for a better prognosis of all forms of CHD. A screening program for CHD should be instituted during the perinatal period. Furthermore, early referral of suspected cases of congenital cardiac anomalies is mandatory for better management till the establishment of cardiac centers in different regions of the continent.

show abstract

Cardiovascular disease in children in Djibouti: a single-centre study

Cited by 10 publications

References 9 publications

Systematic Review of the Manifestations of Congenital Rubella Syndrome in Infants and Characterization of Disability‐Adjusted Life Years (DALYs)

Systematic Review of the Manifestations of Congenital Rubella Syndrome in Infants and Characterization of Disability‐Adjusted Life Years (DALYs)

Profile of Congenital Heart Disease and Access to Definitive Care Among Children Seen at Gulu Regional Referral Hospital in Northern Uganda: a Four-year Experience

Prevalence of congenital septal defects among congenital heart defect patients in East Africa: A systematic review and meta-analysis

Contact Info

Product

Resources

About