Cardiovascular disease (CVD) and its associated risk factors among older adults in India: Evidence from LASI Wave 1

Kundu, Jhumki; Kundu, Sampurna

doi:10.1016/j.cegh.2021.100937

Cited by 36 publications

(19 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Gender plays a vital role, with women being at increased risk of CVDs. 4 According to the data released by the Ministry of Health and Family Welfare (MOHFW) on January 6, 2020, approximately 23% of the elderly individuals (aged ≥60 years) exhibit multi-morbidities. CVDs prevail among 37% of the individuals aged more than 75 years, whereas HTN is reported among 28% of the individuals aged 60-64 years and 35% of those aged 70-74 years.…”

Section: Introductionmentioning

confidence: 99%

Determinants of Adherence to Antihypertensives Among Elderly: A Multifactorial Concern

Sheilini¹,

Hande²,

Devi³

et al. 2022

PPA

View full text Add to dashboard Cite

Purpose The aim of the study was to assess the predictors of adherence among elderly on antihypertensives and to examine the difference in adherence among males and females. Patients and Methods Cross-sectional survey design was adopted for the study. The data were collected from 800 patients of age 60 years and above using demographic proforma, clinical proforma and Morisky Medication Adherence Scale (MMAS-8) with due approval from the institutional ethical clearance committee and written informed consent from the participants. Results The findings revealed no significant difference in the non-adherence rates among males and females. Number of medications was identified as the major predictor of adherence. Conclusion Awareness of factors influencing medication adherence is crucial for health professionals to provide appropriate advice for patients to maintain quality health. The findings of the study highlight the importance of nurses’ role towards imparting knowledge on hypertension and emphasizing on the importance of adherence to antihypertensives among elderly.

show abstract

Section: Introductionmentioning

confidence: 99%

Determinants of Adherence to Antihypertensives Among Elderly: A Multifactorial Concern

Sheilini¹,

Hande²,

Devi³

et al. 2022

PPA

View full text Add to dashboard Cite

show abstract

“…Cardiovascular diseases (CVDs) are a collection of heart and blood vessel ailments that kill over seventeen million people worldwide [ 152 ]. Low-density lipoprotein cholesterol or LDL-C is associated with an increased risk of CVDs [ 153 ] and comprises three proteins (e.g., PCSK9, ApoB, and CETP) that are checkpoint proteins.…”

Section: Resultsmentioning

confidence: 99%

Aspects of Phage-Based Vaccines for Protein and Epitope Immunization

Palma¹

2023

Vaccines

View full text Add to dashboard Cite

Because vaccine development is a difficult process, this study reviews aspects of phages as vaccine delivery vehicles through a literature search. The results demonstrated that because phages have adjuvant properties and are safe for humans and animals, they are an excellent vaccine tool for protein and epitope immunization. The phage genome can easily be manipulated to display antigens or create DNA vaccines. Additionally, they are easy to produce on a large scale, which lowers their manufacturing costs. They are stable under various conditions, which can facilitate their transport and storage. However, no medicine regulatory agency has yet authorized phage-based vaccines despite the considerable preclinical data confirming their benefits. The skeptical perspective of phages should be overcome because humans encounter bacteriophages in their environment all the time without suffering adverse effects. The lack of clinical trials, endotoxin contamination, phage composition, and long-term negative effects are some obstacles preventing the development of phage vaccines. However, their prospects should be promising because phages are safe in clinical trials; they have been authorized as a food additive to avoid food contamination and approved for emergency use in phage therapy against difficult-to-treat antibiotic-resistant bacteria. Therefore, this encourages the use of phages in vaccines.

show abstract

“…The CVD-associated deaths have estimated to 18.6 million in the year 2019 (21). In India, prevalence of CVDs has estimated to 29.4% in the middle age to older population (≥45years age) (22).…”

Section: Prevalence Of Cvdmentioning

confidence: 99%

Circulatory T-cadherin is a potential biomarker for atherosclerosis

et al. 2022

View full text Add to dashboard Cite

T-cadherin, a special member of cadherin family, expresses with blood circulation involving the heart i.e. CVS. Cadherin is connected with the healthy conditions of an individual and normal functioning of cardio-vascular metabolism. T-cadherin is mainly associated with blood vascular system of human. Previous studies analysed this cadherin been unexpressed within the fat storing tissues i.e. adipose tissue of peri-aortic and peri-coronary, it is present within endothelium as well as in vascularized smooth muscular cells which includes the area nearby coronary vessels and aorta. The area and site of this cadherin is attention-grabbing because it particularly related to atherosclerosis and cardiovascular disease (CVD). T-cadherin - a protein acting as the receptor for low density lipoproteins (LDL). It may act as a special biomarker for atherosclerosis. Previous studies on T-cadherin showed that it has cardio-protective role. Furthermore, research is essential to enumerate the cardio-protective function of T-cadherin. It can be an important therapeutic target in developing new medicine to decrease incident of heart disease and its complications.

show abstract

Cardiovascular disease (CVD) and its associated risk factors among older adults in India: Evidence from LASI Wave 1

Cited by 36 publications

References 34 publications

Determinants of Adherence to Antihypertensives Among Elderly: A Multifactorial Concern

Determinants of Adherence to Antihypertensives Among Elderly: A Multifactorial Concern

Aspects of Phage-Based Vaccines for Protein and Epitope Immunization

Circulatory T-cadherin is a potential biomarker for atherosclerosis

Contact Info

Product

Resources

About