Cardiovascular consequences of vaping

Echeagaray, Oscar; Savko, Clarissa; Gallo, Andrea; Sussman, Mark A.

doi:10.1097/hco.0000000000000952

Cited by 9 publications

(8 citation statements)

References 88 publications

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“…For detailed information on the impact of E-cig vaping on the cardiovascular system, please read the excellent reviews covering these subjects. 26 -29 Our results suggest that E-cig exposure leads to cardiovascular dysfunction, such as reductions of cardiac output, and LV positive and negative dp/dt, which may indicate a reduction in contractility and relaxation, and increase in systemic arterial resistance after coronary artery occlusion and reperfusion. In the literature, the effects of E-cig exposure on cardiovascular function remain controversial.…”

Section: Discussionmentioning

confidence: 73%

Effects of Electronic Cigarette Exposure on Myocardial Infarction and No-Reflow, and Cardiac Function in a Rat Model

Dai

Shi

Siddarth

et al. 2023

J Cardiovasc Pharmacol Ther

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Purpose: We investigated the effects of exposure to electronic cigarettes (E-cig) vapor on the sizes of the no-reflow and myocardial infarction regions, and cardiovascular function compared to exposure to purified air and standard cigarette smoke. Methods and Results: Sprague Dawley rats (both male and female, 6 weeks old) were successfully exposed to filtered air (n = 32), E-cig with nicotine (E-cig Nic+, n = 26), E-cig without nicotine (E-cig Nic−, n = 26), or standard cigarette smoke (1R6F reference, n = 31). All rats were exposed to inhalation exposure for 8 weeks, prior to being subjected to 30 minutes of left coronary artery occlusion followed by 3 hours of reperfusion. Exposure to E-cig vapor with or without nicotine or exposure to standard cigarettes did not increase myocardial infarct size or worsen the no-reflow phenomenon. Exposure to E-cig Nic+ reduced the body weight gain, and increased the LV weight normalized to body weight and LV wall thickness and enhanced the collagen deposition within the LV wall. E-cig exposure led to cardiovascular dysfunction, such as reductions in cardiac output, LV positive and negative dp/dt, suggesting a reduction in contractility and relaxation, and increased systemic arterial resistance after coronary artery occlusion and reperfusion in rats compared to air or cigarette exposure. Conclusions: E-cig exposure did not increase myocardial infarct size or worsen the no-reflow phenomenon, but induced deleterious changes in LV structure leading to cardiovascular dysfunction and increased systemic arterial resistance after coronary artery occlusion followed by reperfusion.

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Section: Discussionmentioning

confidence: 73%

Effects of Electronic Cigarette Exposure on Myocardial Infarction and No-Reflow, and Cardiac Function in a Rat Model

Dai

Shi

Siddarth

et al. 2023

J Cardiovasc Pharmacol Ther

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“…Nesse cenário, ressalta-se que o diagnóstico é clínico epidemiológico, relacionando sintomas com o uso dos dispositivos eletrônicos para fumar. Assim, orienta-se a realização de radiografia simples ou tomografia computadorizada de tórax em caso de sintomas mais graves, onde costuma aparecer um padrão de opacidades em vidro fosco com predomínio de bases pulmonares (Shinbashi & Rubin, 2020;Wills et al, 2021;Echeagaray et al, 2022).…”

Section: Discussionunclassified

“…A triagem de lavagem bronquioalveolar de pacientes com EVALI apontou o alfa tocoferol, também conhecido como vitamina E, como a causa potencial da doença devido à sua detecção em 94% dos pacientes com EVALI. Como suplemento ou pomada, a vitamina E geralmente é administrada por via oral ou aplicada na pele e é inofensiva (Larue et al, 2021, Gordon et al, 2022Echeagaray et al, 2022).…”

Section: Introductionunclassified

Prevalência do uso de cigarros eletrônicos e suas complicações respiratórias entre estudantes de medicina em uma universidade privada de Teresina-PI

Lima

Maia

Passos

2023

RSD

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Cigarros eletrônicos (e-cigarros) são dispositivos operados por bateria que permitem aos usuários vaporizar (o ato de insuflar de um cigarro eletrônico) aerossóis contendo nicotina e sabores. O objetivo do estudo é analisar da prevalência do uso de CE entre acadêmicos de medicina, bem como listar e relacionar a presença de sintomas respiratórios com o uso do CE. O estudo foi realizado com uma amostra com 316 participantes acadêmicos de medicina na faixa etária de 18 a 35 anos, que usam ou não cigarros eletrônicos. Os critérios de exclusão serão os alunos que forneceram informações imprecisas e responderam de forma incompleta o questionário. Atualmente, a maioria dos jovens apresentam o conhecimento da existência dos cigarros eletrônicos isso ocorre em consequência da maior disseminação por parte das companhias produtoras de CEs de propagandas agressivas para estimular seu uso. O consumo de CE tem sido associado ao aumento da resistência das vias aéreas periféricas e da fração de óxido nítrico exalado, com características semelhantes aos efeitos da fumaça do tabaco, e à lesão pulmonar associada ao uso de produtos de CE. É fundamental a existência de intervenções que objetivem estimular hábitos saudáveis entre os estudantes e inibam a adoção do uso desse tipo de dispositivo, evitando, em última análise, o aumento do consumo de outros produtos que também liberem nicotina inalada, incluindo derivados de tabaco. Mais pesquisas são necessárias com foco em nas suas consequências, constituintes do e-líquido, características do usuário e padrões de uso.

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“…Additionally, it reached out to law enforcement personnel and held a national review meeting last month. In June 2022, the initial PIL was filed in Rajasthan [ 3 ]. A month later, under the 2019 Prohibition of Electronic Cigarettes (Production, Manufacture, Import, Export, Transport, Sale, Distribution, Storage, and Advertisement) Act, the Jaipur Police conducted raids and booked five individuals.…”

Section: Introductionmentioning

confidence: 99%

Impact of Vaping on Lungs: An Indian Prospect

Sharma,

Jha

2023

Cureus

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Electronic cigarettes, or vape pens, have gained popularity among young people due to their attractive appearance, but they also have numerous side effects. These devices come in various shapes, sizes, and costs, with many brands and various flavors to choose from. As of now, there are around 2,807 people hospitalized in the United States due to vaping. Electronic cigarettes are illegal in many countries, with laws varying from country to country. The health service has been criticized for the implementation of the ban, with states implementing month-long drives and submitting reports. The Indian Police have also conducted raids and arrested five individuals under the 2019 ban on Electronic Cigarettes (Production, Manufacture, Trade, Transport, Sale, Distribution, Storage, and Advertisement) Act. The history of vapes can be traced back to the invention of the first electric vaporizer in 1927 by Joseph Robinson. Other pioneers like Herbert Gilbert and Jed Rose developed nicotine fixes using refined smoke. The vape was made in 2003 by Chinese smoker Hon Lik, who created the device as a better option to traditional smoking.

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Cardiovascular consequences of vaping

Cited by 9 publications

References 88 publications

Effects of Electronic Cigarette Exposure on Myocardial Infarction and No-Reflow, and Cardiac Function in a Rat Model

Effects of Electronic Cigarette Exposure on Myocardial Infarction and No-Reflow, and Cardiac Function in a Rat Model

Prevalência do uso de cigarros eletrônicos e suas complicações respiratórias entre estudantes de medicina em uma universidade privada de Teresina-PI

Impact of Vaping on Lungs: An Indian Prospect

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