Cardiovascular burden and related risk factors among Nunavik (Quebec) Inuit: Insights from baseline findings in the circumpolar Inuit Health in Transition cohort study

Château-Degat, Marie-Ludivine; Dewailly, Éric; Louchini, Rabia; Counil, Émilie; Noël, Martin; Ferland, Annie; Lucas, Michel; BPharm, Béatriz Valera; Ekoé, Jean‐Marie; Ladouceur, Robert; Déry, Steve; Egeland, Grace M.

doi:10.1016/s0828-282x(10)70398-6

Cited by 52 publications

(47 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The existing literature is limited to a 2006 survey based on self-reported data that showed a 3% prevalence among adults aged 15 and older 12 and a 2004 survey of adults in Nunavik, Quebec, that showed a prevalence of 4.7% based on fasting glucose screening and medical chart reviews. 3 Our findings suggest that the prevalence of diabetes among Canadian Inuit is higher than previ-…”

Section: Discussionmentioning

confidence: 62%

“…[1][2][3] A high prevalence of obesity among Canadian Inuit has been noted, 3,4 and yet studies have suggested that the metabolic consequences of obesity may not be as severe among Inuit as they are in predominantly Caucasian or First Nations populations. [4][5][6] Conversely, the prevalence of type 2 diabetes mellitus, which was noted to be rare among Inuit in early studies, 7,8 now matches or exceeds that of predominately Caucasian comparison populations in Alaska and Greenland.…”

mentioning

confidence: 99%

“…[9][10][11] However, in Canada, available reports suggest that diabetes prevalence among Inuit remains below that of the general Canadian population. 3,12 Given the rapid changes in the Arctic and a lack of comprehensive and uniform screening assessments, we used the International Polar Year Inuit Health Survey for Adults 2007-2008 to assess the current prevalence of glycemia and the toll of age and adiposity on glycemia in this population. However, adiposity is heterogeneous, and simple measures of body mass index (BMI) in kg/m 2 and waist circumference do not measure visceral adiposity (or intra-abdominal adipose tissue), which is considered more deleterious than subcutaneous fat.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Hypertriglyceridemic-waist phenotype and glucose intolerance among Canadian Inuit: the International Polar Year Inuit Health Survey for Adults 2007–2008

Gm¹,

Cao²,

Tk³

2011

CMAJ

Self Cite

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 62%

mentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

Hypertriglyceridemic-waist phenotype and glucose intolerance among Canadian Inuit: the International Polar Year Inuit Health Survey for Adults 2007–2008

Gm¹,

Cao²,

Tk³

2011

CMAJ

Self Cite

View full text Add to dashboard Cite

show abstract

“…Food security is defined as when all people at all times have access to sufficient, safe, nutritious food to maintain a healthy and active life (World Food Summit, 1996); when this is not the case, a situation of food insecurity arises. Consequently, increasingly poor nutrition, combined with lifestyle changes such as reduced physical activity and elevated consumption of alcohol and cigarettes, are setting the stage for a major emergence of obesity and diet-sensitive chronic diseases, particularly among Inuit youth and women (Chateau-Degat et al, 2010;Egeland et al, 2011).…”

Section: Implications Of Study Results For the Broader Nunavik Publicmentioning

confidence: 99%

Local country food sources of methylmercury, selenium and omega-3 fatty acids in Nunavik, Northern Quebec

Lemire

Kwan

Laouan-Sidi

et al. 2015

Science of The Total Environment

View full text Add to dashboard Cite

Country foods are central to Inuit culture and replete in selenium (Se) and long-chain omega-3 polyunsaturated fatty acids (n-3 PUFA). However, some marine country foods bioaccumulate high concentrations of methylmercury (MeHg). Se and n-3 are associated with several health benefits in Nunavik, Northern Quebec, but, recent studies show that prenatal MeHg exposure is associated with visual, cognitive and behavioral deficit later in childhood. The study objectives are to identify contemporary country food sources of MeHg, Se and long-chain n-3 PUFA in Nunavik, particularly among childbearing-age women, taking into account regional differences in consumption profiles. The contribution of different country foods to daily MeHg, Se, long-chain n-3 PUFA intake (μg/kg body weight/day) was estimated using: (i) country food consumption and blood biomarkers data from the 2004 Nunavik Health Survey (387 women, 315 men), and (ii) data on MeHg, Se, long-chain n-3 PUFA concentrations found in Nunavik wildlife species. In the region where most traditional beluga hunting takes place in Nunavik, the prevalence of at-risk blood Hg (≥ 8 μg/L) in childbearing-age women was 78.4%. While most country foods presently consumed contain low MeHg, beluga meat, not a staple of the Inuit diet, is the most important contributor to MeHg: up to two-thirds of MeHg intake in the beluga-hunting region (0.66 of MeHg intake) and to about one-third in other regions. In contrast, seal liver and beluga mattaaq - beluga skin and blubber - only mildly contributed to MeHg (between 0.06 and 0.15 of MeHg intake), depending on the region. Beluga mattaaq also highly contributed to Se intake (0.30 of Se intake). Arctic char, beluga blubber and mattaaq, and seal blubber contributed to most long-chain n-3 PUFA intake. This study highlights the importance of considering interconnections between local ecosystems and dietary habits to develop recommendations and interventions promoting country foods' benefits, while minimizing the risk of MeHg from beluga meat, especially for childbearing-age women.

show abstract

“…An individual was defined as having HTN (hypertension) if his/her BP was ≥140/90 mmHg (19) or if he/ she had a previous diagnosis of HTN with or without medication. Hypertension diagnosis was ascertained by individual medical file review as detailed elsewhere (20). The mean of pulse pressure was defined as the difference between systolic blood pressure (SBP) and diastolic blood pressure (DBP).…”

Section: Methodsmentioning

confidence: 99%

Obesity risks: towards an emerging Inuit pattern

Château-Degat

Dewailly

Charbonneau

et al. 2011

International Journal of Circumpolar Health

Self Cite

View full text Add to dashboard Cite

Objectives. The aim of this study was to provide analytical overviews of anthropometric measurements and their relationships with type 2 diabetes and cardiovascular disease (CVD) risk factors within the Inuit population, given that few studies have focused on this issue. Study design. Cross-sectional study. Methods. Anthropometric and biological data were obtained from 867 Inuit participants from Nunavik (≥18 years). Results. Obesity prevalence for men and women, respectively, was 25.1% and 31.3% according to body mass index (BMI: >30 kg/m 2 ); 20.2% and 55.3% according to waist circumference (WC: >102 cm for men and >88 cm for women); 22.4% and 22.5% according to body fat percentage (%BF: ≥30 in men and ≥40 in women). There was substantial agreement between anthropometric obesity measurements, except for the waist-to-hip ratio (WHR) which showed the lowest agreement with the other measurements. All risk factors were significantly associated with anthropometry. The prevalence of abnormal values for risk factors increased across quartiles of BMI and WC. Among obese participants, as defined by the WC cutoff, 22% had metabolic syndrome based on the National Cholesterol Education Program in the Adult Treatment Panel III (NCEP-ATPIII) definition and 64.8% of them were also insulin resistant. Conclusion. Obesity rates among Inuit are high, especially among women. Inuit women display especially high rates of abdominal obesity. Further longitudinal work is needed to evaluate the effects of central and global obesity among Inuit.

show abstract

Cardiovascular burden and related risk factors among Nunavik (Quebec) Inuit: Insights from baseline findings in the circumpolar Inuit Health in Transition cohort study

Abstract: The current belief that the Inuit are protected from CVD is seriously questioned by the results of the present study. Considering the extremely high prevalence of CVD risk factors, a population-based intervention reinforced for women is urgently needed to reduce their risk.

Cited by 52 publications

References 36 publications

Hypertriglyceridemic-waist phenotype and glucose intolerance among Canadian Inuit: the International Polar Year Inuit Health Survey for Adults 2007–2008

Hypertriglyceridemic-waist phenotype and glucose intolerance among Canadian Inuit: the International Polar Year Inuit Health Survey for Adults 2007–2008

Local country food sources of methylmercury, selenium and omega-3 fatty acids in Nunavik, Northern Quebec

Obesity risks: towards an emerging Inuit pattern

Contact Info

Product

Resources

About