Cardiovascular Benefits for Blood Donors? A Systematic Review

Quee, Franke; Peffer, Karlijn; Braake, Anique D. ter; Hurk, Katja van den

doi:10.1016/j.tmrv.2022.04.004

Cited by 2 publications

(3 citation statements)

References 55 publications

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“…This is much higher than results from previous studies in Iran and the United States where between 11% and 38% were motivated by health benefits [24–26]. Several studies conducted to determine the effect of regular blood donation on the heart have been inconsistent and whether or not blood donation protects against cardiovascular diseases remains unclear [27]. This health benefit should therefore be downplayed during blood donation campaigns until definite conclusions are drawn.…”

Section: Discussionmentioning

confidence: 87%

Blood donation among women in Nigeria: Motivators, barriers and appealing incentives

Olawumi,

Fasola,

Otu

et al. 2023

Vox Sanguinis

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Background and Objectives Women are grossly under‐represented among blood donors in Nigeria. We, therefore, determined the barriers, motivators and appealing incentives to blood donation among women in Nigeria. Materials and Methods This was an internet‐based cross‐sectional study among women aged 18–65 years. A well‐structured questionnaire was used to determine sociodemographic characteristics, motivation, barriers and appealing incentives. Motivational and barrier differences in some sociodemographic characteristics were determined using the chi‐squared test. A p‐value of 0.05 was considered statistically significant. Results The most common motivators among blood donors were ‘when family or friend is in need of blood’, ‘health benefits’ and ‘reminders to donate’. One‐time donors who were willing to become regular donors were more motivated by reminders to donate than those not willing (p = 0.000). The most common barriers among non‐donors were ‘poor attitude of hospital staff’ and ‘fear of contracting infections’. Younger women and those of the Hausa tribe were more debarred by ‘lack of privacy during blood donation exercise’ than older women and those of the other tribes (p‐values of 0.008 and 0.006, respectively). The most appealing incentives for blood donation were medical consultation and a blood donation certificate. Conclusion Women's participation in blood donation in Nigeria can be improved by sending regular reminders to donors, especially one‐time donors and by infrastructural adjustments to improve privacy at the blood donation sites. Specific and targeted capacity‐building initiatives should also be put in place to drive a paradigm shift in the attitude of hospital staff to work in Nigeria.

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Section: Discussionmentioning

confidence: 87%

Blood donation among women in Nigeria: Motivators, barriers and appealing incentives

Olawumi,

Fasola,

Otu

et al. 2023

Vox Sanguinis

View full text Add to dashboard Cite

show abstract

“…This review also suggested that studies showing beneficial effects may have inadequately dealt with the HDE. 19 In this study, we examined the possible associations between blood donation and CVD risk in Australian males and females. We examined the risk of CVD in an active donor population using the "qualification period" method similar to that used by Peffer et al, 18 but with further statistical adjustment for measured health differences between the comparison groups.…”

Section: Introductionmentioning

confidence: 99%

“…Overall, a recent systematic review has concluded that studies that have examined the association between blood donation and cardiovascular health show inconsistent results and are generally of poor methodological quality. This review also suggested that studies showing beneficial effects may have inadequately dealt with the HDE 19 …”

Section: Introductionmentioning

confidence: 99%

Regular high‐frequency whole blood donation and risk of cardiovascular disease in middle‐aged and older blood donors in Australia

et al. 2023

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Background: Previous mixed findings on the associations between whole blood (WB) donation and risk of cardiovascular diseases (CVD) may in part reflect inadequate adjustment for the "healthy donor effect" (HDE).Methods: We used the Sax Institute's 45 and Up Study linked with blood donation history and other health-related databases to examine the association between regular, high-frequency WB donation and the risk of CVD. To mitigate the impact of HDE, we used a "5-years qualification period," in which donors must donate at least 1 WB donation in the 1st and 5th year of "qualification period." We then compared the risk of CVD in the years following the "qualification period" between the regular high-frequency WB donors (≥2 WB donation in each qualification year) and others using Cox proportional-hazards models. Analyses were adjusted for potential confounders, such as sociodemographic, lifestyle, and health-related variables, and results are reported separately for male and female donors.Results: A total of 2736 male and 2917 female donors were included in the analyses. The median years of follow-up per donor was 5.84 years (Q1-Q3, 5.47-6.23). The rate of CVD hospitalization was 11.20 and 4.50 per 1000 person-years for males and females, respectively. In fully adjusted models, the risk (hazard ratio) of CVD in regular high-frequency donors compared to other donors was 0.93 (95% Confidence Interval (CI), 0.68-1.29) for males and 0.79 (95% CI, 0.49-1.28) for females.

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Cardiovascular Benefits for Blood Donors? A Systematic Review

Cited by 2 publications

References 55 publications

Blood donation among women in Nigeria: Motivators, barriers and appealing incentives

Blood donation among women in Nigeria: Motivators, barriers and appealing incentives

Regular high‐frequency whole blood donation and risk of cardiovascular disease in middle‐aged and older blood donors in Australia

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