Cardiovascular autonomic function in patients with hemodynamic instability at induction of capnoperitoneum: a case–control study

Abstract

Patients in whom bradycardia and hypotension develop with induction of positive-pressure capnoperitoneum have cardiovascular autonomic dysfunction, which is identifiable by bedside stress tests of autonomic function.

A randomized controlled study evaluating the effects of the temperature of insufflated CO2 on core body temperature and blood gases (an experimental study)

“…Findings have shown that patients with risk factors cannot easily tolerate the probable side effects related to CO 2 insufflation [10][11][12][13][14][15]. Recent studies advocate heated gas usage for the prevention of probable hypothermia caused by routine CO 2 pneumoperitoneum [16][17][18].…”

Quality of Life After Laparoscopic and Open Surgery for Cholecystolithiasis in Patients With Concomitant Cardiovascular Diseases

“…The section of the questionnaire concerning fear prior to planned cholecystectomy showed that patients burdened with cardiovascular diseases and a history of cardiosurgical opera-system focus primarily on the perioperative period, as well as on the effect of the pneumoperitoneum on cardiac function (12). Larsen and co-authors (13) showed similar results in a randomized study concerning the development of the pneumoperitoneum, its duration, and subsequent desufflation in the Trendelenburg and anti-Trendelenburg positions.…”

The role of anticholinergic medication in the prevention of bradycardia during laparoscopic gynaecological surgery

“…Risk factors evaluated included pharmacological, physiological and operative variables. 4,6,8,12,[15][16][17] Two studies demonstrated a significant association between vecuronium and intraoperative bradycardia in laparoscopic surgery and in addition showed a trend toward vecuronium being significantly associated with episodes of asystole; however, they were insufficiently powered. 8,16 This is consistent with previous literature on vecuronium increasing vagal tone.…”

“…4,6,8,12,[15][16][17] Two studies demonstrated a significant association between vecuronium and intraoperative bradycardia in laparoscopic surgery and in addition showed a trend toward vecuronium being significantly associated with episodes of asystole; however, they were insufficiently powered. 8,16 This is consistent with previous literature on vecuronium increasing vagal tone. 19 Given the availability of alternative muscle relaxants, avoiding vecuronium in this setting could be considered.…”