Cardiovascular alterations in eating disorders

Milano, Walter; Capasso, Anna

doi:10.15761/cdm.1000162

Cited by 2 publications

(1 citation statement)

References 23 publications

(49 reference statements)

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“…The study also showed that being underweight was significantly associated with ECG abnormalities. Being Underweight has been linked to QTc prolongation, sinus bradycardia and ventricular arrhythmias (48,49,50,53,54) which could be associated with micronutrients, macronutrients deficiencies, and electrolytes imbalances (49,51,52).…”

Section: Factors Associated With Sinus Bradycardiamentioning

confidence: 99%

Prevalence and factors associated with electrocardiographic abnormalities among adults attending Methadone Assisted Therapy in Dodoma, central Tanzania

Kalungi

Rwiza²,

Nyundo

2022

Preprint

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Background Patients with opioid use disorder are at a higher cardiovascular risk due to the effect of opioids on the cardiovascular system. Cardiac conduction abnormalities, electrical activity impairment, cardiac arrhythmias, and ventricular hypertrophy are reported in the opioid population. Objective This study aimed to assess the prevalence and factors associated with ECG abnormalities among adults with opioid use disorder attending the Itega addiction center for methadone-assisted therapy (MAT). Methodology A cross-sectional analytical study was conducted among adult outpatients attending the Itega addiction center in Dodoma. A calculated sample size of 321was attained through a convenience sampling approach. A standard 12-lead ECG was recorded for each participant and interpreted by two independent cardiologists. Univariate and multivariable logistic regression was computed to determine the factors associated with ECG abnormalities. Under adjusted analysis, a p-value of less than 0.05 was considered significant for factors associated with ECG abnormalities after controlling for all the variables with a minimum p-value of 0.2 at univariate analysis. Results The majority of 308 (95.95%) of the participants were males, 197 (61.37%) had attained primary education level, and the mean age of the participants was 35.44 ± 6.54 years. The overall prevalence for any ECG abnormalities in this study was 26.47%, with Sinus bradycardia 59(18.4%) being the most observed ECG abnormality, followed by QTc prolongation 27(8.41%). A month's increase in the duration on MAT and being a female were significantly associated with lower odds of ECG abnormalities (AOR =0.85, 95% CI =0.74-0.96 p =0.014) and (AOR = 0.05, 95% CI = 0.01-0.59, p = 0.017) respectively. Conclusion The high prevalence of ECG Abnormalities implies high cardiovascular risk among a population with opioid use disorder. Given that majority of the ECG abnormalities are treatable, integrating cardiovascular care in the opioid addiction clinic would be beneficial for this population.

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Section: Factors Associated With Sinus Bradycardiamentioning

confidence: 99%

Prevalence and factors associated with electrocardiographic abnormalities among adults attending Methadone Assisted Therapy in Dodoma, central Tanzania

Kalungi

Rwiza²,

Nyundo

2022

Preprint

View full text Add to dashboard Cite

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Capillaroscopy and Endopat – Helpful Methods for the Early Assessment of Increased Cardiovascular Risk in Anorexia Nervosa?

Ferencova,

Visnovcova,

Ondrejka

et al. 2023

Acta Medica Martiniana

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Anorexia nervosa (AN) as a life-threatening eating disorder is linked to a high mortality risk with many deaths attributable to cardiovascular etiology. Cardiovascular complications in AN include structural as well as functional cardiac alterations, hemodynamic changes, and peripheral vascular abnormalities. Despite the fact that peripheral vascular abnormalities are not identified as a major AN complication, several manifestations of peripheral vascular dysregulation including Raynaud's phenomenon and endothelial dysfunction have been described and, therefore, warrant attention. This article briefly summarizes so far findings of microvascular alterations in AN patients and presents easily accessible and non-invasive procedures for a microvascular evaluation such as capillaroscopy and endothelium-related peripheral arterial tone (EndoPAT) which could be involved in the clinical diagnostic process for the earliest identification of an increased risk of later cardiovascular complications.

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Cardiovascular alterations in eating disorders

Cited by 2 publications

References 23 publications

Prevalence and factors associated with electrocardiographic abnormalities among adults attending Methadone Assisted Therapy in Dodoma, central Tanzania

Prevalence and factors associated with electrocardiographic abnormalities among adults attending Methadone Assisted Therapy in Dodoma, central Tanzania

Capillaroscopy and Endopat – Helpful Methods for the Early Assessment of Increased Cardiovascular Risk in Anorexia Nervosa?

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