Objective Despite the increasing popularity of firsttrimester fetal echocardiography, the evaluation of fetal heart function during this period remains challenging.
chest area ratio and Tei index of the left (LV) and right (RV) ventricles. The proportion of isovolumic contraction (ICT%) and ejection (ET%) times of the cardiac cycle, and the outflow velocities described the systolic function. Diastolic function was evaluated by the proportion of relaxation (IRT%) and filling (FT%) times, the ratio of the blood velocity through the atrioventricular valves during early filling (E) and atrial contraction (A) phases of the cardiac cycle, and ductus venosus pulsatility index for veins (DV-PIV). All participants had additional fetal echocardiography in the second trimester and neonatal clinical examination after birth to confirm normality.
Results The mean heart : chest area ratio (0.203 ± 0.04) and the Tei indices of both ventricles did not vary significantly during weeks 11-14, but the mean
ConclusionWe have established reference ranges for the noninvasive evaluation of fetal cardiocirculatory dynamics at 11-14 weeks' gestation.