Cardiorespiratory responses of air filtration: A randomized crossover intervention trial in seniors living in Beijing

Shao, Danqing; Du, Yipeng; Liu, Shuo; Brunekreef, Bert; Meliefste, Kees; Zhao, Qian; Chen, Jie; Song, Xiaoming; Wang, Meng; Wang, Juan; Xu, Hongbing; Wu, Ruihong; Wang, Tong; Feng, Baihuan; Lung, Candice Shih-Chun; Wang, Xian; He, Ben; Huang, Wei

doi:10.1016/j.scitotenv.2017.06.095

Cited by 75 publications

(69 citation statements)

References 42 publications

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“…During the study period, the concentration of PM 2.5 was 86-140 ug/m 3 in Beijing. Other studies also support the cardiovascular effects of facial mask use to avoid PM, including decreased systolic blood pressure, increased heart rate variability, and reduced ST segment depression (27,36,37), even when considering the confounding effect of traffic noise (38).…”

Section: Discussionmentioning

confidence: 84%

“…Of the seven eligible studies, six were randomized controlled trials (14,15,(23)(24)(25)(26) and one was a randomized cross-over study (27). The study population included asthmatics (14,15,(23)(24)(25)(26) and patients with COPD (27); the study about interstitial lung disease or bronchiectasis was not identified.…”

Section: Study Selection and Characteristicsmentioning

confidence: 99%

“…Six of the identified studies were conducted in North America (14,15,(23)(24)(25)(26); the remaining study was conducted in Beijing, China (27).…”

Section: Study Selection and Characteristicsmentioning

confidence: 99%

“…Four studies analyzed the change in FEV 1 after air filter intervention (14,24,25,27). A randomeffects model yielded a pooled estimate of change in predicted FEV 1 of 3.60% (95% CI: 0.29-6.90%; Fig.…”

Section: Effect Of Air Filter Use On Lung Functionmentioning

confidence: 99%

“…Three studies were judged to have a low risk of bias (14,25,26), two raised some concerns, (15,27). Supplement Table 4.…”

Section: Quality Assessment and Sensitivity Analysismentioning

confidence: 99%

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The effect of particulate matter reduction by indoor air filter use on respiratory symptoms and lung function: A systemic review and meta-analysis

Park

Lee

Suh

et al. 2020

Preprint

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BackgroundExposure to particulate matter (PM) is a key public health issue, but effective intervention has not yet been established. A systematic literature review and meta-analysis has been conducted to assess the relationship between the use of air filters, one of the most-studied interventions, and respiratory outcomes in patients with chronic respiratory disease.MethodsWe systemically reviewed intervention studies on PM using Pubmed, EMBASE, and Cochrane databases up to September 2019. Studies that included data on PM level changes and respiratory symptoms or lung function in patients with respiratory diseases were eligible for inclusion. Effect estimates were quantified separately using the random-effects model.ResultsSeven studies were included in our study. Air filter use reduced indoor PM2.5 by 11.45 µg/m3 (95% confidence interval [CI]: 6.88–16.01 µg/m3). Air filter use improved predicted forced expiratory volume in one second (FEV1) by 3.60% (95% CI: 0.29–6.90%). Air filter use was not associated with a significant change in respiratory symptoms (odds ratio: 0.82; 95% CI: 0.62–1.08).ConclusionThe findings from this systematic review suggest that a role for air filter with respect to reduced indoor PM and increased lung function. Further studies in high density PM regions may provide additional information on this role.Systematic review registration: PROSPERO: on review ID 156258

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