Cardiorespiratory fitness of asthmatic children and validation of predicted aerobic capacity

Abstract

The asthmatic participants presented with lower aerobic capacity than controls in both PAC and MAC; therefore, results confirmed the validity of the PAC method. Data warrant exploration by large-scale paediatric asthma epidemiology.

Predicted Aerobic Capacity of Asthmatic Children: A Research Study from Clinical Origin

“…Earlier results published by my group found lower HR steadystate of the control group than of the asthma group to suggest that physical activity could have influenced HR differently in asthmatic and nonasthmatic children [2]. Even though regressions slopes for HR and VO 2 have been documented to alter with pulmonary disease [27], applying explanations like those to the present asthmatic PAC reductions would involve laboratory replication.…”

“…Laboratory assessment of cardiopulmonary fitness has been documented to require considerable resources whereas the submaximal exercise test overcomes most of these limitations. The PAC-test represented a noninvasive and validated [2] submaximal method and was therefore preferred for the current study.…”

“…The equation applied in this study was validated under the assumption of a linear relationship between VO 2 and HR and the submaximal method tended to underestimate PAC compared with laboratory monitored aerobic capacity [2]. Given such minor underestimation of the present PAC, there has not been an indication that this would have affected the groups in a differential way.…”

“…The estimation used a constant for child resting metabolic rate, RMR, (4.2 mLO 2 /min/kg) [17], and VO 2 (mLO 2 /min/kg). The estimation used laboratory derived VO 2 corresponding to RS at HR steadystate published earlier [2]. …”

“…Children with asthma often experienced breathlessness during physical activity and therefore tended to avoid vigorous physical activity with disadvantageous consequences to their physical conditioning [1, 2]. …”