Cardiorespiratory Disease and Diabetes Among Middle-Aged Male Civil Servants

Reid, D. D.; Hamilton, P. J. S.; Keen, H.; Brett, G.Z.; Jarrett, R. J.; Rose, Geoffrey

doi:10.1016/s0140-6736(74)92783-4

Cited by 316 publications

(148 citation statements)

References 7 publications

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“…This involved the completion of a study questionnaire and participation in a medical examination, both of which have been described in detail elsewhere. 8 In brief, the questionnaire included enquiries regarding civil service employment grade (an indicator of socio-economic position), 12 smoking habits, 13 intermittent claudication, 14 angina, 15,16 chronic bronchitis, 17 marital status, 18 physical activity, 19 unexplained weight loss in the preceding year and the use of drug therapy for heart problem or high blood pressure. 8 Forced expiratory volume in one second (FEV 1 ) adjusted for height, 20 ischaemia, 21 fasting plasma cholesterol, 22 postchallenge 2-h blood glucose, 23 blood pressure, 24 and triceps skinfold thickness 8 were determined using standardised protocols.…”

Section: Methodsmentioning

confidence: 99%

“…(approximately 12.7 mm) below. 8 Weight was recorded with the subject wearing shoes but with jacket removed; readings were taken to the nearest 1 2 lb (227 g). 8 Following conversion from imperial to metric units, BMI (weight (kg) divided by height squared (m 2 )) was computed.…”

Section: Methodsmentioning

confidence: 99%

“…8 Weight was recorded with the subject wearing shoes but with jacket removed; readings were taken to the nearest 1 2 lb (227 g). 8 Following conversion from imperial to metric units, BMI (weight (kg) divided by height squared (m 2 )) was computed. To facilitate comparability of our findings with those from other studies, [26][27][28] we defined underweight (o18.5 to 25.0 kg/m 2 ), normal weight (BMI 18.5 to o25.0 kg/m 2 ), overweight (25.0-29.99 kg/m 2 ) and obesity (Z30.0 kg/m 2 ), according to criteria advanced by the World Health Organisation.…”

Section: Methodsmentioning

confidence: 99%

“…8 In an extended (maximum 35 y) mortality surveillance of this cohort, there have been over 3000 cancer deaths, enabling us to address these issues of data scarcity and methodological shortcomings.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Obesity and overweight in relation to organ-specific cancer mortality in London (UK): findings from the original Whitehall study

Batty

Shipley

Jarrett³

et al. 2005

Int J Obes

125

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OBJECTIVE:To examine the relation of obesity and overweight with organ-specific cancer mortality. METHODS: In the Whitehall prospective cohort study of London-based government employees, 18 403 middle-age men participated in a medical examination between 1967 and 1970. Subjects were followed up for cause-specific mortality for up to 35 y (median: interquartile range (25th-75th centile); 28.1 y: 18.6-33.8). RESULTS: There were over 3000 cancer deaths in this cohort. There was a raised risk of mortality from carcinoma of the rectum, bladder, colon, and liver, and for lymphoma in obese or overweight men following adjustment for range of covariates, which included socioeconomic position and physical activity. These relationships held after exclusion of deaths occurring in the first 20 y of follow-up. CONCLUSION: Avoidance of obesity and overweight in adult life may reduce the risk of developing some cancers.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Obesity and overweight in relation to organ-specific cancer mortality in London (UK): findings from the original Whitehall study

Batty

Shipley

Jarrett³

et al. 2005

Int J Obes

125

View full text Add to dashboard Cite

show abstract

“…The methods of the study have been previously reported [6]. Men known to be diabetic could participate in the screening survey, but were not required to take the oral glucose load.…”

Section: Methodsmentioning

confidence: 99%

Type 2 (non-insulin-dependent) diabetes mellitus and cardiovascular disease ? putative association via common antecedents; further evidence from the whitehall study

Jarrett¹,

Shipley

1988

Diabetologia

160

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Summary. Fifteen year mortality rates are reported for men participating in the Whitehall Study in 1968-70. Subjects were divided into four groups -normoglycaemic (centiles 1-95 of the blood glucose distribution: n=17,05t), glucose intolerant (centiles96-100: n=999), newly diagnosed diabetic patients (n= 56) and previously diagnosed diabetic patients (n= 121) treated with diet + tablets. Relative risks for all causes mortality-and from coronary and cardiovascular disease deaths were calculated. Age adjusted relative risks were highest in the newly diagnosed diabetic patients and were also increased in glucose intolerant and previously diagnosed diabetic men (p< 0.05), but did not increase with increasing duration of diabetes. With adjustment for other risk factors, relative risks were similar in newly diagnosed and previously diagnosed diabetic men. There was no significant linear trend of adjusted relative risks with duration of diabetes when all diabetic men were pooled and person years at risk calculated. The lack of effect of duration upon relative risk together with other observations suggests common, possibly genetic, antecedents of both Type 2 (non-insulin-dependent) diabetes and coronary heart disease.

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Impact of Smoking Cessation Advice on Future Smoking Behavior, Morbidity, and Mortality: Up to 40 Years of Follow-up of the First Randomized Controlled Trial of a General Population Sample

Batty

Shipley²,

Kivimäki³

et al. 2011

Arch Intern Med

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Cardiorespiratory Disease and Diabetes Among Middle-Aged Male Civil Servants

Cited by 316 publications

References 7 publications

Obesity and overweight in relation to organ-specific cancer mortality in London (UK): findings from the original Whitehall study

Obesity and overweight in relation to organ-specific cancer mortality in London (UK): findings from the original Whitehall study

Type 2 (non-insulin-dependent) diabetes mellitus and cardiovascular disease ? putative association via common antecedents; further evidence from the whitehall study

Impact of Smoking Cessation Advice on Future Smoking Behavior, Morbidity, and Mortality: Up to 40 Years of Follow-up of the First Randomized Controlled Trial of a General Population Sample

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