“… 2 CKD resulting in chronic HF is known as cardiorenal syndrome (CRS) type 4 3 and has been increasingly identified as a marker of higher morbidity and mortality. 1 , 4 Left ventricular hypertrophy (LVH) and diastolic dysfunction are the major factors contributing to development of heart failure with preserved ejection fraction (HFpEF) and sudden cardiac death through ischemia and arrhythmia. 5 A linear relationship between worsening glomerular filtration rate and LV function confers poor clinical outcomes and the highest mortality.…”