Cardiopulmonary exercise testing for detecting pulmonary arterial hypertension in systemic sclerosis

Dumitrescu, Daniel; Nagel, Christian; Kovàcs, Gabór; Bollmann, Tom; Halank, Michael; Winkler, Jörg; Hellmich, Martin; Grünig, Ekkehard; Olschewski, Horst; Ewert, Ralf; Rosenkranz, Stephan

doi:10.1136/heartjnl-2016-309981

Cited by 67 publications

(77 citation statements)

References 24 publications

(27 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Very recently, Dumitrescu et al demonstrated in patients with systemic sclerosis that peak VO 2 and VE/VCO 2 had a high correlation with PAP, TPG and PVR.…”

Section: Discussionmentioning

confidence: 98%

Cardiopulmonary exercise test predicts right heart catheterization

Correale

Tricarico

Ferraretti

et al. 2017

Eur J Clin Investigation

View full text Add to dashboard Cite

show abstract

“…Very recently, Dumitrescu et al demonstrated in patients with systemic sclerosis that peak VO 2 and VE/VCO 2 had a high correlation with PAP, TPG and PVR.…”

Section: Discussionmentioning

confidence: 98%

Cardiopulmonary exercise test predicts right heart catheterization

Correale

Tricarico

Ferraretti

et al. 2017

Eur J Clin Investigation

View full text Add to dashboard Cite

show abstract

“…Reddy et al 31 demonstrated that, in the differentiation of HFpEF from patients with noncardiac dyspnea, there was significant overlap in peak O 2 consumption alone without invasive measures (Figure 1). nCPET may be useful diagnostically, however, only when targeted to specific at-risk populations such as scleroderma patients 32 or those in whom PH is suspected by echocardiograpy. 33 Data from nCPET incrementally predicts mortality when added to resting hemodynamics.…”

Section: Methodsmentioning

confidence: 99%

Tools of the Trade: How Do You Perform and Interpret an Exercise Test?

Rischard

Borlaug

2019

Advances in Pulmonary Hypertension

View full text Add to dashboard Cite

Background: Most pulmonary vascular disease (PVD) is poorly modifiable and incurable even with effective therapy. Therefore, adaptation to stress, the reserve of the cardiopulmonary system, is important for assessment of patient function and prognosis. Methods that assess the adaptation to stress, especially exercise, provide valuable insight into diagnosis, prognosis, and response to therapy. Implications for Clinicians: We provide a comprehensive review of the indications, methodology, and interpretation, as well as practical information of the forms of provocative testing in PVD. We include 6-minute walk testing, noninvasive cardiopulmonary exercise testing (CPET), invasive CPET, and additional forms, including volume loading. Conclusions: Through a clear understanding of the methodology in the assessment of PVD, the clinician can determine which of these "tools of the trade" are best suited to the individual patient and situation.

show abstract

“…Eine Hypoxämie in Ruhe kann unter Belastung zunehmen, insbesondere bei Auftreten eines Rechts-Links-Shunts bei steigendem rechtsatrialem Druck und offenem Foramen ovale [189,191]. Diese charakteristischen Befundmuster können bei einem Teil symptomatischer Sklerodermiepatienten auch mit unauffälligen echokardiografischen Befunden gesehen werden [192], sodass spiroergometrische Parameter der Leistungsfähigkeit (peak V O 2 ) und der Atemeffizienz (Nadir V E/V CO 2 ) relevante Aussagen zur Abschätzung der Wahrscheinlichkeit einer PAH bei symptomatischen Sklerodermiepatienten treffen können [193].…”

Section: Neue Parameter Der Spiroergometrieunclassified

Belastungsuntersuchungen in der Pneumologie – Empfehlungen der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin e. V.

et al. 2018

View full text Add to dashboard Cite

ZusammenfassungDieses Dokument der DGP ersetzt die Empfehlungen von 1998 und 2013. Anhand der aktuellen Datenlage und einer Konsensuskonferenz wurden Empfehlungen zu Indikationen, zur Auswahl und Durchführung der geeigneten Belastungsuntersuchungen sowie zu den technischen und personellen Voraussetzungen formuliert. Detaillierte Angaben werden zur Blutgasanalyse unter Belastung, zu Gehtests und Rechtsherzkatheter unter Belastung sowie zur Spiroergometrie und Stressechokardiografie gemacht. Der korrekte Einsatz von Belastungsuntersuchungen bei anstrengungsinduziertem Asthma, bei sport-, arbeits- bzw. rehabilitationsmedizinischen Fragestellungen, bei Adipositas, bei der präoperativen Risikostratifizierung und beim Therapiemonitoring pneumologischer Erkrankungen wird dargestellt.

show abstract

Cardiopulmonary exercise testing for detecting pulmonary arterial hypertension in systemic sclerosis

Abstract: CPET is a safe and valuable method in the non-invasive detection of SSc-associated PAH. It may be particularly beneficial for reducing unnecessary RHC procedures.

Cited by 67 publications

References 24 publications

Cardiopulmonary exercise test predicts right heart catheterization

Cardiopulmonary exercise test predicts right heart catheterization

Tools of the Trade: How Do You Perform and Interpret an Exercise Test?

Belastungsuntersuchungen in der Pneumologie – Empfehlungen der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin e. V.

Contact Info

Product

Resources

About