“…Rodrigues et al [20] studied the effect of intermittent administration of cardioplegic solution in hypothermia or SILVEIRA FILHO, LM ET AL -Trimetazidine as cardioplegia addictive without pre-treatment does not improve myocardial protection: study in a swine working heart model normothermia in a model of acutely ischemic isolated working rabbit heart. This same group [21], achieving to evidence effects of addition of glutamate and aspartate in intermittent cardioplegic solution did not find significant differences between the two treatments.…”