Cardioneuroablation of the right anterior ganglionated plexus in symptomatic sinus bradycardia after extensive weight loss

Reek, David; Deiss, M.; Bouchikhi, Hind El

doi:10.1093/europace/euab331

Cited by 3 publications

(1 citation statement)

References 3 publications

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“…Dr. Yao et al mainly ablated the groups of GP sites in the left atrium in the CNA procedure [ 12 , 20 ], while Dr. Debruyne et al only targeted the groups of GP sites in the right atrium [ 21 , 22 ]. Published studies also indicated the potential feasibility of the CNA procedure only focusing on the ablation of RAGP or Ao-SVC GP [ 21 , 35 ]. Concurrently, groups of GP sites in both the left atrium and the right atrium were ablated by Dr. Pachon et al [ 9 , 18 , 23 ] and Dr. Aksu et al [ 13 , 15 , 16 ] during their CNA procedures.…”

Section: Discussionmentioning

confidence: 99%

Extracardiac Vagal Stimulation-Assisted Cardioneuroablation: Dynamically Evaluating the Impact of Sequential Ganglionated Plexus Ablation on Vagal Control of SAN and AVN in Patients with Sinoatrial Node Dysfunction

Chen

Liu

Xiao

et al. 2022

JCDD

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Cardioneuroablation (CNA) is proposed as a promising therapy for patients with sinoatrial node dysfunction (SND) that is mediated by excessive vagal tone. However, a series of urgent questions about CNA remain unanswered. From December 2020 to March 2022, six patients with symptomatic SND who underwent CNA were summarized in this report. Sequential CNA targeting Ao-SVC GP, PMLGP, RAGP, and LSGP was performed in patients, guided by fractionated intracardiac electrograms and dynamically evaluated by extracardiac vagal stimulation (ECVS). The results showed that Ao-SVC GP ablation led to a significant increase in heart rate (HR) and the elimination of sinus arrest evoked by ECVS, while the vagal responses of atrial ventricular block were eliminated by the ablation of PMLGP and LSGP. Post-procedure HR increased up to 64–86% of the maximum HR of an atropine test at baseline. The median HR from Holter monitoring increased from 52.8 ± 2.1 bpm at baseline to 73.0 ± 10.4 bpm after the procedure (p = 0.012) and to 71.3 ± 10.1 bpm at the six-month follow-up (p = 0.011). Bradycardia-related symptoms disappeared in all patients at the six-month follow-up. This case series reveals the feasibility of using the ECVS-assisted sequential CNA technique and indicates the critical role of ECVS in dynamically evaluating the impact of sequential CNA on the vagal control of SAN and AVN.

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Section: Discussionmentioning

confidence: 99%

Extracardiac Vagal Stimulation-Assisted Cardioneuroablation: Dynamically Evaluating the Impact of Sequential Ganglionated Plexus Ablation on Vagal Control of SAN and AVN in Patients with Sinoatrial Node Dysfunction

Chen

Liu

Xiao

et al. 2022

JCDD

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Neuromodulation for Vasovagal Syncope and Bradyarrhythmias

Khan,

Huang,

Aksu

2024

Cardiac Electrophysiology Clinics

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Twenty-five years of research on syncope

Fedorowski,

Kulakowski,

Brignole

et al. 2023

Europace

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Over the last 25 years, the Europace journal has greatly contributed to dissemination of research and knowledge in the field of syncope. More than 400 manuscripts have been published in the journal. They undoubtedly improved our understanding of syncope. This symptom is now clearly differentiated from other forms of transient loss of consciousness. The critical role of vasodepression and/or cardioinhibition as final mechanisms of reflex syncope is emphasized. Current diagnostic approach sharply separates between cardiac and autonomic pathways. Physiologic insights have been translated, through rigorously designed clinical trials, into non-pharmacological or pharmacological interventions and interventional therapies. The following manuscript is intended to give the reader the current state of the art of knowledge of syncope by highlighting landmark contributions of the Europace journal.

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Cardioneuroablation of the right anterior ganglionated plexus in symptomatic sinus bradycardia after extensive weight loss

Cited by 3 publications

References 3 publications

Extracardiac Vagal Stimulation-Assisted Cardioneuroablation: Dynamically Evaluating the Impact of Sequential Ganglionated Plexus Ablation on Vagal Control of SAN and AVN in Patients with Sinoatrial Node Dysfunction

Extracardiac Vagal Stimulation-Assisted Cardioneuroablation: Dynamically Evaluating the Impact of Sequential Ganglionated Plexus Ablation on Vagal Control of SAN and AVN in Patients with Sinoatrial Node Dysfunction

Neuromodulation for Vasovagal Syncope and Bradyarrhythmias

Twenty-five years of research on syncope

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