Cardioneuroablation - Bradyarrhythmias Treatment by Catheter RF Ablation without PM Implantation

Pachón, E.I.; Lobo, Tasso J.; Pachón, Juan Carlos; Zelia, M.; Pachón, Carlos Thiene Cunha; Vargas, Remy Nélson Albornoz; Piegas, Leopoldo Soares; Jatene, Adib

doi:10.1016/j.eupc.2005.08.015

Cited by 2 publications

(3 citation statements)

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“…At present, the majority of CNA procedures are being performed in patients with neuromediated cardioinhibitory syncope and then in patients with functional bradyarrhythmias. There is limited data on the use of the CNA procedure in the context of a functional atrioventricular block (FAVB), especially in clinical cases or case series (12,13). These patients, even without any organic damage to the conduction system, often present disabling symptoms with a significant reduction in the quality of life; treatment with drugs and/or pacemakers provides poor results.…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, pacemaker implantation is not well accepted and is accompanied by significant psychological discomfort, in addition to a risk of infection and long-term ventricular desynchronization. The absence of an organic disease, as well as a presumed benign course of the disease, makes the decision to carry out implantation more difficult (12). Therefore, a strategy like the one described in this study could represent a solution to the problem.…”

Section: Discussionmentioning

confidence: 99%

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A case report of cardiac neuromodulation in a young patient with a third-degree atrioventricular block

Valenti,

Di Monaco,

Romanazzi

et al. 2024

Front. Cardiovasc. Med.

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BackgroundThere are some functional bradyarrhythmias that are caused by a dysregulation of the autonomic nervous system, for which a therapeutic strategy of cardioneuroablation (CNA) is conceivable.Case summaryIn this study, we report the case of a 19-year-old woman with a non-congenital third-degree atrioventricular block (AVB), symptomatic for lipothymia and dyspnea caused by mild exertion. She had a structurally normal heart and no other comorbidities. The atropine test and the exercise stress test documented a sinus tachycardia at 190 bpm with a 2:1 AVB, a narrow QRS, and an atrioventricular conduction of 1:1 until reaching a sinus rhythm rate of 90 bpm. She underwent the CNA procedure, which targeted the inferior paraseptal ganglion plexus, with a gradual change in the ECG levels recorded during the radiofrequency delivery from a third-degree AVB to a first-degree AVB. After the procedure, we observed a complete regression of the third-degree AVB, with evidence of only a first-degree AVB and a complete regression of symptoms until the 6-month follow-up.ConclusionsAlthough not yet included in current guidelines, the CNA procedure could be used to treat AV node dysfunction in young subjects, as it could represent an alternative to pacemaker implantation. However, more randomized studies are needed to assess the long-term efficacy of this promising technique.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

A case report of cardiac neuromodulation in a young patient with a third-degree atrioventricular block

Valenti,

Di Monaco,

Romanazzi

et al. 2024

Front. Cardiovasc. Med.

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“…We will simulate the rolling process of a single sphere and the formation process of a three-dimensional particle pile under certain conditions, in order to obtain some results different from those without considering the rotation resistance. These research results will help to deeply understand the motion behavior of granular materials, and provide theoretical guidance and practical application value for related engineering and natural phenomena [1][2][3][4].…”

Section: Introductionmentioning

confidence: 88%

Research on rotational resistance in particle motion simulation based on discrete element method

2024

mpcr

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In this paper, the effect of rotational resistance on particle motion in discrete element method is studied. In the discrete element method, the interaction between particles is simulated by point contact, and the mechanical constitutive model of contact action is established by a set of normal and tangential springs and dampers for each contact point. However, in the process of contact between particles, there are not only the normal and tangential forces that affect the relative translation of particles, but also the torque effect that affects the mutual rotation of particles. In this paper, the effect of rotating resistance on particle motion is studied by adding rotating spring and rotating damper to the contact point model. The rolling process of a single sphere and the formation process of a threedimensional particle pile under certain conditions are simulated, and some results are obtained which are different from those without considering the rotation resistance. These results have some guiding significance for the motion behavior of granular materials in nature and engineering.

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Cardioneuroablation - Bradyarrhythmias Treatment by Catheter RF Ablation without PM Implantation

Cited by 2 publications

References 0 publications

A case report of cardiac neuromodulation in a young patient with a third-degree atrioventricular block

A case report of cardiac neuromodulation in a young patient with a third-degree atrioventricular block

Research on rotational resistance in particle motion simulation based on discrete element method

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