Cardiometabolic Health in Obese Adolescents Is Related to Length of Obesity Exposure: A Pilot Study

Abstract

Increased cardiometabolic risk in boys is related to an earlier onset and a longer duration of obesity.

Fasting insulin resistance affects the prevalence of metabolically healthy obesity in Brazilian adolescents

“…. Although the association between pubertal stage and metabolic status has not been found by some authors , metabolic alterations during the sexual maturation process have been consistently described in the literature . It is important to acknowledge that we were limited in our sample size for this categorical variable, which may have reduced our statistical power and precision to detect differences between obesity phenotypes.…”

“…The current study added to this knowledge base by examining the associations between obesity level adjusting for gender and pubertal stage categories and by differentiating the two definitions, including insulin resistance. We recognise, though, that our study would have been further strengthened by studying the association of the duration and timing of the onset of obesity , as well as fat mass degree and distribution , with metabolic phenotypes.…”

Metabolically healthy obesity across the life course: epidemiology, determinants, and implications

“…and Camhi et al . defined obesity as a BMI greater than or equal to the 95th percentile, and Zamrazilova et al . used a BMI greater than or equal to the 97th percentile to classify obesity.…”

“…Blood among children and adolescents. [14][15][16][17][18][19][20] While metabolic health may be simply defined as the absence of insulin resistance, 17 in the majority of studies MHO characterization centers on the absence of MetS (or some of its cardiometabolic risk factors) [14][15][16][17][18][19][20] among those with excess body weight. It is important to note that how obesity is classified is also an issue, with different anthropometric measures and cutoffs being used.…”

“…It is important to note that how obesity is classified is also an issue, with different anthropometric measures and cutoffs being used. The Bogalusa Heart Study defined overweight/obesity as a BMI in the top quartile, 16 the cross-sectional study by Prince et al 17 defined obesity as a BMI greater than or equal to the 85th percentile, the studies by Vukovic et al 18,19 and Camhi et al 14,21 defined obesity as a BMI greater than or equal to the 95th percentile, and Zamrazilova et al 20 used a BMI greater than or equal to the 97th percentile to classify obesity. The Korean Children-Adolescent Study was based on abdominal obesity assessed by waist circumference (WC).…”