Feline aortic thromboembolism is a cardiovascular disease that affects the feline species, with acute paralysis being one of the forms of clinical presentation. The objective of this clinical case is to describe the clinical and therapeutic management of a cat with acute paralysis due to aortic thromboembolism. A general physical examination and complementary tests were performed to diagnose aortic thromboembolism and subsequent pharmacological treatment associated with the surgical intervention. It is concluded that it is possible to reverse acute paralysis due to thromboembolism through definitive diagnosis and initiation of thrombolytic treatment associated with the surgical procedure.