Cardioactive compounds from Eremophila species

Interesting biological activities from plants traditionally used by Native Australians

“…That study led to the isolation of a phenylethanoid glycoside called verbascoside (syn. acteoside and kusaginin) (Pennacchio et al, 1996a). Verbascoside significantly increased heart rate, contractile force and coronary perfusion rate in isolated Langendorff rat hearts.…”

“…Australian and other researchers have only just started to realize the extent of this knowledge, much of which was lost following European colonization. A number of subsequent studies have recently revealed that some of the plants used by Native Australians produce useful biologically active compounds (Pennacchio et al, 1995(Pennacchio et al, , 1996a(Pennacchio et al, ,b, 1999Wickens and Pennacchio, 2002). We now report on the interesting antibiotic and cardioactive properties that arose from an investigation of four routinely used plant species.…”

Cardioactive Agents from Plants

“…Phenolic glycoside (6-O-galloyl-D-glucose) contained in the leaves of Sapium sebiferum (Euphorbiaceae) showed hypotensive action appears to be produced by an inhibition of noradrenaline release and/or a direct vasodilatation [52]. Moreover, chlorogenic acid in green coffee bean extract reduced blood pressure in spontaneously hypertensive rats and humans.…”

Plant‐derived medicinal entomochemicals: an integrated approach to biodiscovery in Australia

“…In addition, leaf and flower extracts have been shown to modulate platelet activity involved in the aetiology of migraine, supporting their traditional use as a headache remedy (Rogers et al ). Geniposidic acid, a non‐volatile iridoid glycoside isolated from the leaves is reported to have cardioactive properties (Pennacchio et al ).…”

“…microtheca † Witchetty grubs (M, F); Lerps (Psyllidae) (F); Galls (Eriococcidae) (F) (Deegan et al 2010;Latz 2018) Colds, flu, internal pains, joint pain, skin sores, pruritus, headache (L, B); toothache, medicinal wash (B) (ACNT 1993;Peile and Bindon 1997;Bordulk et al 2012) Antibacterial, antifungal, antioxidant, insecticidal (L) (Ghaffar et al 2015;Maghsoodlou et al 2015;Nikbakht et al 2015;Siddique et al 2017Siddique et al , 2018 Saponins (B); terpenoid essential oils (e.g. 1,8cineole and α-pinene) (L, F) (ACNT 1993;Bignell et al 1997;Ghaffar et al 2015;Maghsoodlou et al 2015;Nikbakht et al 2015;Siddique et al 2017Siddique et al , 2018 Eucalyptus intertexta (Floater 1996;Walsh et al 2014) Sores, burns, cuts (G) (Bindon 1996) Antitumour activity (L, St) (Collins et al 1990 (ACNT 1993;Bindon 1996;Latz 2018) Antimicrobial, antioxidant (L, Sm, St); modulation of platelet activity (antiheadache) (L, F); cardioactive effects (L) (Pennacchio et al 1996;Rogers et al 2000;Hayhoe and Palombo 2011;Sadgrove et al 2011;Singab et al 2013; Terpenoid essential oils, iridoid glucoside (geniposidic acid), alkaloids, phenylpropanoids (L); genifuranal (Sm); phenolics (St) (Pennacchio et al 1996;Sadgrove et al 2011;Singab et al 2013; References are provided within each subheading. Note: the terms 'witchetty/edible grubs', 'lerp' and so forth may constitute many different species.…”