Cardiac transplantation for hypertrophic cardiomyopathy in the United States 2003–2011

Vallabhaneni, Srilakshmi; Singh, Amitoj; Meera, Srinidhi J.; Shirani, Jamshid

doi:10.4103/ijciis.ijciis_82_19

Cited by 2 publications

(1 citation statement)

References 28 publications

(6 reference statements)

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“…Despite these limitations, hospital discharge databases based on ICD codes have been used widely in epidemiological research by many authors from various countries. Such databases have proven useful for studying temporal trends as well as the characteristics, procedures, and hospital outcomes of HT recipients [9,11,37,[47][48][49][50].…”

Section: Discussionmentioning

confidence: 99%

Temporal trends and outcomes of heart transplantation in Spain (2002–2021): propensity score matching analysis to compare patients with and without type 2 diabetes

Lopez-de-Andres,

Jiménez-García,

Hernández-Barrera

et al. 2023

Cardiovasc Diabetol

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Background The impact of Type 2 Diabetes (T2D) on the outcomes of heart transplantation (HT) has not yet been clearly established. The objectives of this study were to examine the trends in the prevalence of T2D among individuals who underwent a HT in Spain from 2002 to 2021, and to compare the clinical characteristics and hospitalization outcomes between HT recipients with and without T2D. Methods We used the national hospital discharge database to select HT recipients aged 35 and older. The International Classification of Diseases, Ninth and Tenth Revisions (ICD-9 and ICD-10) were used to identify patients with and without T2D. We also recorded comorbidities, complications of HT, and procedures. Propensity score matching (PSM) and Cox regression were used to analyze the effect of T2D on in-hospital mortality (IHM). Results Between 2002 and 2021, a total of 4429 HTs (T2D, 19.14%) were performed in Spain. The number of HTs in patients with T2D decreased from 2002 to 2005 (n = 171) to 2014–2017 (n = 154), then rose during 2018–2021 (n = 186). Complications of HT increased in patients with and without T2D over the study period (26.9% and 31.31% in 2002–2005 vs. 42.47% and 45.01% in 2018–2021, respectively). The results of the PSM showed that pneumonia and Gram-negative bacterial infections were less frequent in patients with T2D and that these patients less frequently required hemodialysis, extracorporeal membrane oxygenation (ECMO), and tracheostomy. They also had a shorter hospital stay and lower IHM than patients without diabetes. The variables associated with IHM in patients with T2D were hemodialysis and ECMO. IHM decreased over time in people with and without T2D. The Cox regression analysis showed that T2D was associated with lower IHM (HR 0.77; 95% CI 0.63–0.98). Conclusions The number of HTs increased in the period 2018–2021 compared with 2002–2005 in patients with and without T2D. Over time, complications of HT increased in both groups studied, whereas IHM decreased. The presence of T2D is associated with lower IHM.

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Section: Discussionmentioning

confidence: 99%

Temporal trends and outcomes of heart transplantation in Spain (2002–2021): propensity score matching analysis to compare patients with and without type 2 diabetes

Lopez-de-Andres,

Jiménez-García,

Hernández-Barrera

et al. 2023

Cardiovasc Diabetol

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Accuracy of administrative database estimates of national surgical volume: Solid organ transplantation in the National Inpatient Sample

Fielding‐Singh

Grogan

Neelankavil

2021

Clinical Transplantation

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Background:Little is known about the accuracy of procedural coding in the National Inpatient Sample, in part because it is challenging to validate population-level estimates. Methods:We evaluated the accuracy of the National Inpatient Sample by comparing estimates of solid organ transplantation to known national transplant volumes from the Organ Procurement and Transplant Network. Results:The mean deviation of National Inpatient Sample point estimates from true transplant volume for the study period was 17.5 ± 20.8%. The mean deviation of point estimates from 2005 to 2011 was 26.4 ± 22.8% compared to 4.9 ± 6.3% from 2012 to 2016 (P < .001). Conclusions:Although future National Inpatient Sample transplantation research may be limited by the inability to subgroup procedures by donor type, surgical procedure coding of solid organ transplantation within the National Inpatient Sample appears to be accurate and reliable for generating national estimates, particularly after the National Inpatient Sample redesign in 2012.

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Cardiac transplantation for hypertrophic cardiomyopathy in the United States 2003–2011

Cited by 2 publications

References 28 publications

Temporal trends and outcomes of heart transplantation in Spain (2002–2021): propensity score matching analysis to compare patients with and without type 2 diabetes

Temporal trends and outcomes of heart transplantation in Spain (2002–2021): propensity score matching analysis to compare patients with and without type 2 diabetes

Accuracy of administrative database estimates of national surgical volume: Solid organ transplantation in the National Inpatient Sample

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