Cardiac transplantation for cancer involving the heart

Wingo, Matthew; Biasi, Andreas R. de; Shudo, Yasuhiro; Bharathi, Vijaya; Blackburn, A. C.; Gaudino, Mario; Girardi, Leonard N.; Woo, Y. Joseph

doi:10.1016/j.healun.2020.05.010

Cited by 3 publications

(1 citation statement)

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“…This is particularly true if there are indications of malignancy, a risk of embolization or a mechanical complication of the heart valve. The indication for heart transplantation in malignant heart tumors is controversial [17]. However, there are also reports of favorable outcomes in primary malignant heart tumors after aggressive multimodality treatment [18].…”

Section: Discussionmentioning

confidence: 99%

Rare Case Report: Left Atrial Sarcoma Obstructing the Left Ventricular Inflow

Kaemmerer,

Suleiman,

Agaimy

et al. 2023

JCM

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Malignant cardiac tumors of the heart are extremely rare and may present tremendous diagnostic and therapeutic challenges. These tumors are able to infiltrate the heart and metastasize systemically. Early detection is often elusive as the clinical presentation is highly variable, posing significant diagnostic and therapeutic difficulties. Despite a multidisciplinary approach, the prognosis for patients with malignant cardiac tumors remains guarded. Early diagnosis and a multidisciplinary approach involving cardiac surgeons, oncologists and critical care specialists are crucial in the management of this disease. Further research is needed to better understand the pathomechanisms of tumor-related complications and to develop effective treatment strategies to improve patient outcomes. The rare case of a 78-year-old woman with left atrial tumor requiring emergency surgery for acutely developing mitral valve obstruction is presented. Pathology confirmed an undifferentiated pleomorphic sarcoma. This patient tragically did not survive, highlighting the difficulties of managing such a rare and deceptive heart disease.

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Section: Discussionmentioning

confidence: 99%