Cardiac tamponade due to hypothyroidism: a case cluster report

Coetzee, André; Kyriakakis, Charles; Greyling, Chris; Ascott-Evans, Brynne

doi:10.1080/16089677.2016.1191243

Cited by 6 publications

(10 citation statements)

References 12 publications

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“…This is most likely due to concurrent addisonian crisis in APS-II patients at the time of pericarditis. Thyroid and adrenal hormone deficiencies may cause the retention of free water due to increased capillary permeability, and cases of cardiac tamponade in patients with hypothyroidism have been reported (11). In addition, sepsis in patients with APS-II can present with a similar clinical picture with cardiac tamponade, thus a thorough infectious work up is important.…”

Section: Discussionmentioning

confidence: 99%

Autoimmune Polyglandular Syndrome Type II as a Cause of Recurrent Cardiac Tamponade

Park

Dimachkie

Gruntmanis

2017

AACE Clinical Case Reports

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Objective: This study reports an unusual presentation of autoimmune polyglandular syndrome type II (APS-II) with recurrent cardiac tamponade due to pericarditis in a young male patient. Methods: We report clinical presentation, laboratory data, and imaging studies for our patient. Relevant literature is reviewed. Results: Our patient was a 29-year-old Hispanic man with a history of primary hypothyroidism who presented to the emergency department complaining of chest pain and found to have cardiac tamponade due to pericardial effusion. He rapidly became hemodynamically unstable and underwent pericardiocentesis, after which he was admitted to the intensive care unit. The patient gradually recovered and was discharged after 15 days of hospitalization, while the etiology of his illness remained unclear. Four months later, he again presented with similar symptoms and was diagnosed with recurrent cardiac tamponade. He became hemodynamically unstable, and underwent pericardiocentesis. His morning serum cortisol level was found to be undetectable and further workup confirmed autoimmune etiology of primary adrenal insufficiency. The presence of hypothyroidism, vitiligo, and subsequent adrenal insuf-ficiency in the context of positive glutamic acid decarboxylase antibody suggested the diagnosis of APS-II in our patient. Conclusion: APS-II has many associated complications. Cardiac tamponade is a rare presentation of APS-II but it is crucial to recognize it because recurring pericarditis and cardiac tamponade can be fatal in these patients. Accurate diagnosis and timely hormone replacement with monitoring for cardiac complications can prevent fatal outcomes. (AACE Clinical Case Rep. 2017;3:e353-e356) Abbreviations: APS-II = autoimmune polyglandular syndrome type II; ED = emergency department; T1DM = type 1 diabetes mellitus e354 APS-II and Cardiac Tamponade, AACE Clinical Case Rep. 2017;3(No. 4)

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Section: Discussionmentioning

confidence: 99%

Autoimmune Polyglandular Syndrome Type II as a Cause of Recurrent Cardiac Tamponade

Park

Dimachkie

Gruntmanis

2017

AACE Clinical Case Reports

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“…Pericardial effusion is common in hypothyroidism, with prevalence ranging from 3% in mild disease to 80% when myxoedema is present, but large pericardial effusion causing tamponade is relatively rare 1. The most common symptoms of hypothyroidism include weight gain, fatigue, cold intolerance, constipation, dry skin, oedema, muscular weakness and reduced deep tendon reflexes.…”

Section: Descriptionmentioning

confidence: 99%

“…The classic Beck’s triad of cardiac tamponade includes jugular venous distension, hypotension and distant heart sounds with associated tachycardia and pulsus paradoxus 1. In general, tachycardia is usually present in an attempt to maintain cardiac output.…”

Section: Descriptionmentioning

confidence: 99%

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Impending cardiac tamponade as a primary presentation of Hashimoto’s thyroiditis

et al. 2018

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“…(1,2) Incidence of pericardial effusion caused by hypothyroidism are around 3-37% and it mainly occurs on severe hypothyroidism but no data about cardiac tamponade. (3,4) Diagnosis of hypothyroidism as a cause of pericardial effusion is made if related to increased TSH and other secondary causes have been ruled out. Early recognition of thyroid disorder can prevent complication and mediate prompt treatment.…”

Section: Introductionmentioning

confidence: 99%

Cardiac Tamponade in a Patient With Hypothyroidism: A Case Report

Hermifa Dwi Aninnaimah,

Sony Wibisono

2021

Indian Journal of Forensic Medicine & Toxicology

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Cardiac tamponade as a manifestation in newly diagnosed hypothyroidism is a rare condition because fluid accumulate slowly. We present a 38-year-old woman with massive pericardial effusion with cardiac tamponade findings in echocardiography without hemodynamic disturbance. Pericardiocentesis was done, but pericardial effusion was not improved. Other secondary causes of pericardial effusion including inflammation, infection, autoimmune disease, and malignancy were ruled out. The patient had a history of thyroidectomy 4 years prior and thyroid function test confirm the diagnosis of hypothyroidism. The patient was given levothyroxine with initial dose of 400 mcg and continued with 100 mcg daily. The pericardial effusion significantly improved in a week.

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Cardiac tamponade due to hypothyroidism: a case cluster report

Cited by 6 publications

References 12 publications

Autoimmune Polyglandular Syndrome Type II as a Cause of Recurrent Cardiac Tamponade

Autoimmune Polyglandular Syndrome Type II as a Cause of Recurrent Cardiac Tamponade

Impending cardiac tamponade as a primary presentation of Hashimoto’s thyroiditis

Cardiac Tamponade in a Patient With Hypothyroidism: A Case Report

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