Cardiac Tamponade as the Initial Manifestation of Systemic Lupus Erythematosus

Mohseni, Michael; Rogers, Ethan R.

doi:10.1016/j.jemermed.2010.05.041

Cited by 4 publications

(3 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“… Pericardiocentesis, NSAIDs, oral steroids and antimalarial drugs. 6 Mohseni et al [ 26 ] 14 F Diagnosed at autopsy; serositis, elevated ANA and anti-dsDNA titres. Pericardiocentesis.…”

Section: Discussionmentioning

confidence: 99%

Cardiac tamponade as the initial presentation of systemic lupus erythematosus: a case report and review of the literature

Maharaj

Chang

2015

Pediatr Rheumatol

View full text Add to dashboard Cite

Systemic lupus erythematosus (SLE) is an autoimmune disease that can involve any organ system, exhibiting great diversity in presentation. Cardiac tamponade as the initial presentation of childhood onset SLE (cSLE) is rare. We report the case of a 10 year old Afro-Caribbean female who presented with complaints of chest pain, shortness of breath and fever over 4 days. Clinical examination strongly suggested cardiac tamponade which was confirmed by investigations and treated with pericardiocentesis. After a thorough investigation, the underlying diagnosis of SLE was confirmed using the Systemic Lupus International Collaborating Clinics (SLICC) criteria and high dose corticosteroid therapy initiated. A review of recent studies shows that common initial presentations of cSLE include constitutional symptoms, renal disease, musculoskeletal and cutaneous involvement. In presenting this case and reviewing the literature we emphasize the importance of cSLE as a differential diagnosis when presented with pericarditis in the presence or absence of cardiac tamponade. In these patients early diagnosis and treatment is desired and in this regard we also discuss the sensitivity of the SLICC criteria in cSLE.Electronic supplementary materialThe online version of this article (doi:10.1186/s12969-015-0005-0) contains supplementary material, which is available to authorized users.

show abstract

“… Pericardiocentesis, NSAIDs, oral steroids and antimalarial drugs. 6 Mohseni et al [ 26 ] 14 F Diagnosed at autopsy; serositis, elevated ANA and anti-dsDNA titres. Pericardiocentesis.…”

Section: Discussionmentioning

confidence: 99%

Cardiac tamponade as the initial presentation of systemic lupus erythematosus: a case report and review of the literature

Maharaj

Chang

2015

Pediatr Rheumatol

View full text Add to dashboard Cite

show abstract

“…It develops when the pressure inside the pericardial space increases to more than the pressure in the cardiac chambers leading to reduction in diastolic filling, in cardiac output and in systemic blood pressure. Its diagnosis should be suspected clinically in any child presenting with respiratory distress and cardiopulmonary compromise; however, the definite diagnosis is made by echocardiography 1 2. It usually follows progressive pericardial effusion that may occur secondary to several infectious and non-infectious aetiologies.…”

Section: Discussionmentioning

confidence: 99%

“…All the reported cases required treatment with immediate pericardiocentesis and were discharged on oral steroid therapy. In case number 3,1 the diagnosis of SLE was made on autopsy. That case had a fulminant disease after a 4-day history of upper respiratory tract symptoms.…”

Section: Discussionmentioning

confidence: 99%

Cardiac tamponade as the first manifestation of systemic lupus erythematosus in children: Table 1

et al. 2012

View full text Add to dashboard Cite

SummarySystemic lupus erythematosus (SLE) is a serious chronic autoimmune disease with intense inflammatory response and damage in many target organs including joints, skin, kidneys, heart and nervous system. Cardiac tamponade is extremely rare as a cardinal presentation of SLE in children with only a few cases reported in the literature. We report two cases of a 9-year-old boy and an 11-year-old girl presenting with acute cardiac tamponade and later recognition of elevated anti-double-stranded DNA (anti-dsDNA) titre. We also present a literature review about similar cases in children and we stress on the importance of screening all cases of acute cardiac tamponade in children with antinuclear and anti-dsDNA antibodies to avoid any delay in SLE diagnosis and treatment. BACKGROUND

show abstract