muscularly only to 17 patients. In addition, sulfadiazine was used in all but 1 of the cases and the specific rabbit serum was administered to 17 patients and aureomycin to 1 patient. Of the 90 patients, 87 recovered and 3 died, a recovery rate of 96.6 per cent. The 17 patients treated with intramuscular but without intraspinal injections of streptomycin recovered completely. With regard to the adjunctive therapy, it was difficult to evaluate the role of sulfadiazine. There was no evi¬ dence that rabbit serum played a contributory role. There were relatively few toxic reactions in the series, and neurologic residua occurred in a small number of the cases. Several important problems require further investigation, particularly those pertaining to the occur¬ rence of sequelae and the method of choice in strepto¬ mycin therapy.